Abstract
The development of microfluidics and its utilization in a myriad of applications has grown exponentially over the past 15 years. One area that has benefited from the great strides in fabrication of microelectromechanical systems (MEMS) is separations chemistry. Most studies have focused on small molecule and DNA separations; few on protein chromatographic techniques on microchips. This review details recent developments in protein separations on microfluidic platforms and how MEMS have the potential for revolutionizing protein chromatography.
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Acknowledgments
The authors gratefully acknowledge financial support for this research by grants from the National Science Foundation (CHE-0515363 and DMR-0351848).
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Gomez, F.A. (2011). Microfluidics in Protein Chromatography. In: Walls, D., Loughran, S. (eds) Protein Chromatography. Methods in Molecular Biology, vol 681. Humana Press. https://doi.org/10.1007/978-1-60761-913-0_8
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DOI: https://doi.org/10.1007/978-1-60761-913-0_8
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