Analysis of Autophagy for Liver Pathogenesis
The autophagy pathway in hepatocytes is well characterized. Autophagy plays a critical role in the normal function of the liver. A growing number of studies suggest that there is a mechanistic relationship between autophagy and the pathogenesis of human diseases including liver diseases. Here we focus on the methods assessing the level of lipids, lipid peroxidation, and lipophagy in the liver, which would be particularly relevant to the study of fatty liver diseases.
Key wordsAutophagy Fatty liver diseases Hepatocytes Immunofluorescence Lipid droplets Lipophagy Reactive oxygen species