Abstract
Esophagogastrectomy for esophageal adenocarcinoma remains a procedure of significant morbidity and mortality rates. Management should be within the context of a multidisciplinary team. Appropriate patient selection, careful preoperative preparation, meticulous application of surgical technique and perioperative care are essential for success. Enhanced recovery after surgery (ERAS) protocols are evidence based and improve outcome. Standard protocol for open transthoracic esophagectomy is described.
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References
Siewert JR, Stein HJ (1998) Classification of adenocarcinoma of the esophagogastric junction [see comments]. Br J Surg 85(11):1457–1459
Omloo JM, Lagarde SM, Hulscher JB, Reitsma JB, Fockens P, van Dekken H, ten Kate FJ, Obertop H, Tilanus HW, van Lanschot JJ (2007) Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the mid/distal esophagus: five-year survival of a randomized clinical trial. Ann Surg 246(6):992–1000
Sasako M, Sano T, Yamamoto S, Sairenji M, Arai K, Kinoshita T, Nashimoto A, Hiratsuka M (2006) Left thoracoabdominal approach versus abdominal-transhiatal approach for gastric cancer of the cardia or subcardia: a randomised controlled trial. Lancet Oncol 7(8):644–651
Law S (2012) Esophagogastrectomy for carcinoma of the esophagus. In: Fischer J (ed) Mastery of surgery, 6th edn. Wolters Kluweer, Lippincott Williams & Wilkins, Philadelphia, pp 886–903
Shapiro J, van Lanschot JJ, Hulshof MC, van Hagen P, van Berge Henegouwen MI, Wijnhoven BP, van Laarhoven HW, Nieuwenhuijzen GA, Hospers GA, Bonenkamp JJ, Cuesta MA, Blaisse RJ, Busch OR, Ten Kate FJ, Creemers GJ, Punt CJ, Plukker JT, Verheul HM, Bilgen EJ, van Dekken H, van der Sangen MJ, Rozema T, Biermann K, Beukema JC, Piet AH, van Rij CM, Reinders JG, Tilanus HW, Steyerberg EW, van der Gaast A, group Cs (2015) Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for esophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial. Lancet Oncol 16(9):1090–1098. https://doi.org/10.1016/S1470-2045(15)00040-6
van Hagen P, Hulshof MC, van Lanschot JJ, Steyerberg EW, van Berge Henegouwen MI, Wijnhoven BP, Richel DJ, Nieuwenhuijzen GA, Hospers GA, Bonenkamp JJ, Cuesta MA, Blaisse RJ, Busch OR, ten Kate FJ, Creemers GJ, Punt CJ, Plukker JT, Verheul HM, Spillenaar Bilgen EJ, van Dekken H, van der Sangen MJ, Rozema T, Biermann K, Beukema JC, Piet AH, van Rij CM, Reinders JG, Tilanus HW, van der Gaast A, Group C (2012) Preoperative chemoradiotherapy for esophageal or junctional cancer. N Engl J Med 366(22):2074–2084. https://doi.org/10.1056/NEJMoa1112088
Cunningham D, Allum WH, Stenning SP, Thompson JN, van de Velde CJ, Nicolson M, Scarffe JH, Lofts FJ, Falk SJ, Iveson TJ, Smith DB, Langley RE, Verma M, Weeden S, Chua YJ, Magic TP (2006) Perioperative chemotherapy versus surgery alone for resectable gastresophageal cancer. N Engl J Med 355(1):11–20
Allum WH, Stenning SP, Bancewicz J, Clark PI, Langley RE (2009) Long-term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer. J Clin Oncol 27(30):5062–5067. https://doi.org/10.1200/JCO.2009.22.2083
Weimann A, Braga M, Carli F, Higashiguchi T, Hubner M, Klek S, Laviano A, Ljungqvist O, Lobo DN, Martindale R, Waitzberg DL, Bischoff SC, Singer P (2017) ESPEN guideline: clinical nutrition in surgery. Clin Nutr 36(3):623–650. https://doi.org/10.1016/j.clnu.2017.02.013
Markar SR, Karthikesalingam A, Low DE (2015) Enhanced recovery pathways lead to an improvement in postoperative outcomes following esophagectomy: systematic review and pooled analysis. Dis Esophagus 28(5):468–475. https://doi.org/10.1111/dote.12214
Findlay JM, Gillies RS, Millo J, Sgromo B, Marshall RE, Maynard ND (2014) Enhanced recovery for esophagectomy: a systematic review and evidence-based guidelines. Ann Surg 259(3):413–431. https://doi.org/10.1097/SLA.0000000000000349
Law S, Boey JP, Kwok KF, Wong KH, Chu KM, Wong J (2004) Pleural drainage after transthoracic esophagectomy: experience with a vacuum system. Dis Esophagus 17(1):81–86
Tsui SL, Law S, Fok M, Lo JR, Ho E, Yang J, Wong J (1997) Postoperative analgesia reduces mortality and morbidity after esophagectomy. Am J Surg 173(6):472–478
Murthy SC, Law S, Whooley BP, Alexandrou A, Chu KM, Wong J (2003) Atrial fibrillation after esophagectomy is a marker for postoperative morbidity and mortality. J Thorac Cardiovasc Surg 126(4):1162–1167
Whooley BP, Law S, Murthy SC, Alexandrou A, Wong J (2001) Analysis of reduced death and complication rates after esophageal resection. Ann Surg 233(3):338–344
Zehetner J, DeMeester SR, Alicuben ET, Oh DS, Lipham JC, Hagen JA, DeMeester TR (2015) Intraoperative assessment of perfusion of the gastric graft and correlation with anastomotic leaks after esophagectomy. Ann Surg 262(1):74–78. https://doi.org/10.1097/SLA.0000000000000811
Law S, Fok M, Chu KM, Wong J (1997) Comparison of hand-sewn and stapled esophagogastric anastomosis after esophageal resection for cancer: a prospective randomized controlled trial. Ann Surg 226(2):169–173
Law S, Suen DT, Wong KH, Kwok KF, Wong J (2005) A single-layer, continuous, hand-sewn method for esophageal anastomosis: prospective evaluation in 218 patients. Arch Surg 140(1):33–39
Whooley BP, Law S, Alexandrou A, Murthy SC, Wong J (2001) Critical appraisal of the significance of intrathoracic anastomotic leakage after esophagectomy for cancer. Am J Surg 181(3):198–203
Lo OS, Law S, Chu KM, Wong J (2003) Chylothorax after esophagectomy. Surgery 133(3):340–341
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Law, S. (2018). Surgical Protocol for Esophageal Adenocarcinoma. In: Lam, A. (eds) Esophageal Adenocarcinoma. Methods in Molecular Biology, vol 1756. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7734-5_4
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DOI: https://doi.org/10.1007/978-1-4939-7734-5_4
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