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Nutritional Programming Effects on Development of Metabolic Disorders in Later Life

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Investigations of Early Nutrition Effects on Long-Term Health

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1735))

Abstract

Developmental programming resulting from maternal malnutrition can lead to an increased risk of metabolic disorders such as obesity, insulin resistance, type 2 diabetes and cardiovascular disorders in the offspring in later life. Furthermore, many conditions linked with developmental programming are also known to be associated with the aging process. This review summarizes the available evidence about the molecular mechanisms underlying these effects, with the potential to identify novel areas of therapeutic intervention. This could also lead to the discovery of new treatment options for improved patient outcomes.

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Authors and Affiliations

  1. Department of Food and Experimental Nutrition, Food Research Center (FoRC) and Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil

    Thomas Prates Ong

  2. Laboratory of Neuroproteomics, Institute of Biology, University of Campinas, Campinas, Brazil

    Paul C. Guest

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  1. Thomas Prates Ong
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  2. Paul C. Guest
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Correspondence to Paul C. Guest .

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  1. Debden, Essex, United Kingdom

    Paul C. Guest

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Ong, T.P., Guest, P.C. (2018). Nutritional Programming Effects on Development of Metabolic Disorders in Later Life. In: Guest, P. (eds) Investigations of Early Nutrition Effects on Long-Term Health. Methods in Molecular Biology, vol 1735. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7614-0_1

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  • DOI: https://doi.org/10.1007/978-1-4939-7614-0_1

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