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Compassionate Use of Bacteriophage Therapy for Foot Ulcer Treatment as an Effective Step for Moving Toward Clinical Trials

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Bacteriophage Therapy

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1693))

Abstract

We here present detailed descriptions of successful treatment of a series of diabetic toe ulcers using the Eliava BioPreparations’ commercial preparation of the very well-studied anti-staphylococcal bacteriophage Sb-1. This chapter outlines what we feel is an appropriate mechanism to speed movement toward full-scale clinical trials with bacteriophage use to treat wound infections and to help address the crisis in antibiotic resistance.

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Author information

Authors and Affiliations

  1. PhageBiotics Research Foundation, Gray’s Harbor Community Hospital, Aberdeen, WA, USA

    Randolph Fish, Elizabeth Kutter & Gordon Wheat

  2. Wound Centers at St Joseph’s Medical Center, Tacoma, WA, USA

    Randolph Fish

  3. Bacteriophage Lab – The Evergreen State College, Evergreen Parkway NW, Olympia, WA, 98505, USA

    Elizabeth Kutter

  4. Kaiser Permanente Northwest, Saint Peter Hospital Family Medicine Residency, 3324 Sunset Beach Dr., Olympia, WA, 98502, USA

    Gordon Wheat

  5. Laboratory of Gene Technology, KU Leuven, Kasteelpark Arenberg, 21, Belgium

    Bob Blasdel

  6. George Eliava Institute of Bacteriophages, Microbiology and Virology – 3, Gotua str., Tbilisi, 0160, GA, USA

    Mzia Kutateladze

  7. VA Northern California, Muir Road, Martinez, CA, 94553, USA

    Sarah Kuhl

  8. University of California, San Francisco, CA, USA

    Sarah Kuhl

Authors
  1. Randolph Fish
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  2. Elizabeth Kutter
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  3. Gordon Wheat
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  4. Bob Blasdel
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  5. Mzia Kutateladze
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  6. Sarah Kuhl
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Corresponding author

Correspondence to Randolph Fish .

Editor information

Editors and Affiliations

  1. LIBRO-Laboratory of Research in Biofilms Rosário Oliveira, CEB – Centre of Biological Engineering, University of Minho, Braga, Portugal

    Joana Azeredo

  2. CEB – Centre of Biological Engineering, University of Minho, Braga, Portugal

    Sanna Sillankorva

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Fish, R., Kutter, E., Wheat, G., Blasdel, B., Kutateladze, M., Kuhl, S. (2018). Compassionate Use of Bacteriophage Therapy for Foot Ulcer Treatment as an Effective Step for Moving Toward Clinical Trials. In: Azeredo, J., Sillankorva, S. (eds) Bacteriophage Therapy. Methods in Molecular Biology, vol 1693. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7395-8_14

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  • DOI: https://doi.org/10.1007/978-1-4939-7395-8_14

  • Published:

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7394-1

  • Online ISBN: 978-1-4939-7395-8

  • eBook Packages: Springer Protocols

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