Big data for randomized trials

In this topical collection (13 articles)

1. Study protocol

   Preoperative dexamethasone administration in hepatectomy of 25-min intermittent Pringle’s maneuver for hepatocellular carcinoma: protocol for a randomized controlled trial

   Yang Huang, Liangliang Xu, Ning Wang, Xingyu Pu, Wentao Wang, Tianfu Wen… Article:774

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2. Review

   A systematic review identifying common data items in neonatal trials and assessing their completeness in routinely recorded United Kingdom national neonatal data

   Sena Jawad, Neena Modi, A. Toby Prevost, Chris Gale Article:731

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3. Study protocol

   Electronic health record nested pragmatic randomized controlled trial of a reminder system for serum lithium level monitoring in patients with mood disorder: KONOTORI study protocol

   Tomotsugu Seki, Morio Aki, Hirotsugu Kawashima, Tomotaka Miki, Shiro Tanaka… Article:706

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4. Study protocol

   Integrated traditional Chinese medicine intervention for delaying HIV morbidity: study protocol for a multicentre randomised controlled trial

   Xue Ding, Pengfei Meng, Xiuxia Ma, Weifeng Cui, Liangping Li, Xiyuan Song… Article:665

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5. Commentary

   Core outcome sets through the healthcare ecosystem: the case of type 2 diabetes mellitus

   Susanna Dodd, Nicola Harman, Nichole Taske, Mark Minchin, Toni Tan… Article:570

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6. Study protocol

   Effect of probiotic supplementation on in-hospital mortality in patients with acute myocardial infarction: a study protocol for an open-label, randomized, controlled, superiority clinical trial

   Yequn Chen, Rongbing Chen, Xin Wang, Yan Zhou, Liekai Hong, Nianling Xiong… Article:429

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7. Research

   Access to routinely collected health data for clinical trials – review of successful data requests to UK registries

   Sarah Lensen, Archie Macnair, Sharon B. Love, Victoria Yorke-Edwards… Article:398

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8. Study protocol

   Safety and efficacy in pediatric secondary intraocular lens implantation, in-the-bag versus sulcus implantation: a multicenter, single-blinded randomized controlled trial

   Yingshi Zou, Ling Jin, Bo Qu, Hui Chen, Mingbing Zeng, Xia Li, Xinhua Liu… Article:388

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9. Methodology

   Using electronic patient records to assess the effect of a complex antenatal intervention in a cluster randomised controlled trial—data management experience from the DESiGN Trial team

   Sophie Relph, Maria Elstad, Bolaji Coker, Matias C. Vieira, Natalie Moitt… Article:195

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10. Study protocol

    Safety and efficacy comparison of polyethylene glycol, hemp seed oil, and 5% sugar brine for bowel preparation in older patients: study protocol for a randomized controlled trial

    Xing Wang Zhu, Jun Yan, Long Miao, Ying Li He, Hai Ping Wang, Xun Li Article:168

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11. Methodology

    Online randomized controlled experiments at scale: lessons and extensions to medicine

    Ron Kohavi, Diane Tang, Ya Xu, Lars G. Hemkens, John P. A. Ioannidis Article:150

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12. Study protocol

    Total laparoscopic partial hepatectomy versus open partial hepatectomy for primary left-sided hepatolithiasis: study protocol for a randomized controlled trial

    Shu-bo Pan, Chun-li Wu, Da-chen Zhou, Qi-ru Xiong, Xiao-ping Geng, Hui Hou Article:137

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13. Study protocol

    Effectiveness of IT-supported patient recruitment: study protocol for an interrupted time series study at ten German university hospitals

    Martin Boeker, Daniela Zöller, Romina Blasini, Philipp Macho, Sven Helfer… Article:125

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