Theme: Heterotrimeric G Protein-based Drug Development: Beyond Simple Receptor Ligands

In this topical collection (7 articles)

1. Mini-Review

   Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands

   Camillo Rosano, Marco Ponassi, Maria Francesca Santolla, Assunta Pisano… Pages 41-46

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2. Review Article

   R4 Regulator of G Protein Signaling (RGS) Proteins in Inflammation and Immunity

   Zhihui Xie, Eunice C. Chan, Kirk M. Druey Pages 294-304

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3. Review Article

   Recent Advances on the Role of G Protein-Coupled Receptors in Hypoxia-Mediated Signaling

   Rosamaria Lappano, Damiano Rigiracciolo, Paola De Marco, Silvia Avino… Pages 305-310

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4. Review Article

   Regulator of G-protein Signaling (RGS)1 and RGS10 Proteins as Potential Drug Targets for Neuroinflammatory and Neurodegenerative Diseases

   Jae-Kyung Lee, Josephine Bou Dagher Pages 545-549

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5. 

   Review Article

   Regulator of G Protein Signaling 17 as a Negative Modulator of GPCR Signaling in Multiple Human Cancers

   Michael P. Hayes, David L. Roman Pages 550-559

6. 

   Review Article

   RGS6 as a Novel Therapeutic Target in CNS Diseases and Cancer

   Katelin E. Ahlers, Bandana Chakravarti, Rory A. Fisher Pages 560-572

7. 

   Review Article

   The EP3 Receptor/G_z Signaling Axis as a Therapeutic Target for Diabetes and Cardiovascular Disease

   Michael D. Schaid, Jaclyn A. Wisinski, Michelle E. Kimple Pages 1276-1283