Theme: Process Analytical Technology (PAT) in Pharmaceutical and Biopharmaceutical Industry

In this topical collection (6 articles)

1. 

   Research Article

   NIR Spectroscopy as an Online PAT Tool for a Narrow Therapeutic Index Drug: Toward a Platform Approach Across Lab and Pilot Scales for Development of a Powder Blending Monitoring Method and Endpoint Determination

   Sameer Talwar, Pallavi Pawar, Huiquan Wu, Koushik Sowrirajan, Suyang Wu… Article:103

2. 

   Research Article

   Phase-appropriate Application of Process Analytical Technology for Early Pharmaceutical Development of Oral Solid Dosage Forms—the Case Study of Uniformity Screening of Dosage Units and Blends

   Sayyeda Zeenat Razvi, Shengli Ma, Qiqing Zhong, Ariel Muliadi… Article:90

3. 

   Research Article

   Process Analytical Technology (PAT) Implementation for Membrane Operations in Continuous Manufacturing of mAbs: Model-Based Control of Single-Pass Tangential Flow Ultrafiltration

   Garima Thakur, Vishnu Masampally, Amey Kulkarni, Anurag S. Rathore Article:83

4. 

   Research Article

   Comparison Between Pure Component Modeling Approaches for Monitoring Pharmaceutical Powder Blends with Near-Infrared Spectroscopy in Continuous Manufacturing Schemes

   Adam J. Rish, Samuel R. Henson, Md. Anik Alam, Yang Liu… Article:82

5. Review Article

   Application of Artificial Neural Networks in the Process Analytical Technology of Pharmaceutical Manufacturing—a Review

   Brigitta Nagy, Dorián László Galata, Attila Farkas… Article:74

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6. 

   Research Article

   Development of a Near-Infrared Spectroscopy (NIRS)–Based Characterization Approach for Inherent Powder Blend Heterogeneity in Direct Compression Formulations

   Zhenqi Shi, Kallakuri Suparna Rao, Prajwal Thool, Robert Kuhn… Article:9