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Production of Chimeric Chickens

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Germ Cell Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 254))

Abstract

Somatic and germline chimeric chickens are very useful for studying various biological functions of cells, such as immune rejection of donor cells in recipient embryos and chickens, or analyzing the developmental fate of transferred donor cells into recipients. Production of germline chimeric chickens makes it possible to manipulate germline cells in vitro (e.g., DNA transfer or cryopreservation), and the manipulated germline cells can allow viable offspring by germline chimeric chickens. It is expected that endangered avian species can also proliferate via interspecific germline chimeric chickens.

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Author information

Authors and Affiliations

  1. Animal Genetic Engineering Laboratory, Developmental Biology Department, National Institute of Agrobiological Sciences, Tsukuba, Japan

    Mitsuru Naito

  2. Pathology Section, National Institute for Minamata Disease, Minamata, Japan

    Takashi Kuwana

Authors
  1. Mitsuru Naito
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  2. Takashi Kuwana
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Editor information

Editors and Affiliations

  1. Department of Veterinary Pathobiology, University of Missouri-Columbia, Columbia, MO

    Heide Schatten

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© 2004 Humana Press Inc.

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Naito, M., Kuwana, T. (2004). Production of Chimeric Chickens. In: Schatten, H. (eds) Germ Cell Protocols. Methods in Molecular Biology™, vol 254. Humana Press. https://doi.org/10.1385/1-59259-741-6:245

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  • DOI: https://doi.org/10.1385/1-59259-741-6:245

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-257-5

  • Online ISBN: 978-1-59259-741-3

  • eBook Packages: Springer Protocols

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