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The principles of organ storage procedures

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Organ Preservation

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Abstract

A period of ischaemia is inevitable in any organ transplantation procedure; the duration may be brief, perhaps 20min when a living donor is used, but it is always total, and more usually it lasts a number of hours, sometimes days. The function, then, of preservation methods, is to prevent ischaemic damage. Ischaemia should be carefully differentiated from anoxia and hypoxia, the total or partial lack of oxygen; anoxia is merely one of the many consequences of lack of a blood supply. The effects of ischaemia are best discussed after first considering the normal functions of the blood circulation. What follows is elementary and familiar, but it provides the essential foundation for an analysis of preservation methods.

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Authors
  1. D. E. Pegg
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Editors and Affiliations

  1. MRC Medical Cryobiology Group, University Department of Surgery, Douglas House,Trumpington Road, CB2 2AH, Cambridge, UK

    D. E. Pegg

  2. Department of Nephrology, University Hospital, DK-5000, Odense C, Denmark

    I. A. Jacobsen

  3. Department of Surgery, University of California Medical Center, 225 Dickinson Street, 92103, San Diego, California, USA

    N. A. Halasz

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© 1982 MTP Press Limited

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Pegg, D.E. (1982). The principles of organ storage procedures. In: Pegg, D.E., Jacobsen, I.A., Halasz, N.A. (eds) Organ Preservation. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6267-8_6

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  • DOI: https://doi.org/10.1007/978-94-011-6267-8_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-011-6269-2

  • Online ISBN: 978-94-011-6267-8

  • eBook Packages: Springer Book Archive

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