Abstract
Problems associated with hypoxic tissue damage emerge as central constraints in cardiovascular, neurosurgical and transplantation surgery. Achievements in these fields have been predominantly the results of advances in surgical techniques, medical and intensive-care methods.
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References
Hossmann, K. A. and Kleihues, P. (1973). Reversibility of ischemic brain damage. Arch. Neurol., 29, 375
Kalimo, H., Garcia, J.H., Kamijyo, Y., Tanaka, J. and Trump, F. (1977). The ultra- structure of ‘brain death’. II. Electron microscopy of feline cortex after complete ischaemia. Virchows Arch. B. Cell Pathol., 25, 207
Rehncrona, S., Mela, L. and Siesjô, B.K. (1979). Recovery of brain mitochondrial function in the rat after complete and incomplete cerebral ischaemia. Stroke, 10, 437
Hearse, D. J., Humphrey, S.M., Naylor, W.G., Slade, A. and Border, D. (1975). Ultra- structural damage associated with reoxygenation of the anoxic myocardium. J. Molec. Cardiol., 7, 315
Buckberg, G.D. (1979). A proposed ‘solution’ to the cardioplegic controversy. J. Thorac. Cardiovasc. Surg., 77, 803
Hearse, D. J., Stewart, D.A. and Braimbridge, M. V. (1976). Cellular protection during myocardial ischemia. The development and characterization of a procedure for the induction of reversible ischemic arrest. Circulation, 54, 193
Summers, W.K. and Jamison, R.L. (1971). The no reflow phenomenon in renal ischemia. Lab. Invest., 25, 635
Majno, G., Ames, III, A., Chiang, J. and Wright, R. L. (1967). No reflow after cerebral ischemia. Lancet, 2, 635
Willerson, J. T., Powell, W.J. Jr, Gruiney, T.E., Stark, J. I., Saunders, C. A. and Leaf, A. (1972). Improvement in myocardial function and coronary blood flow in ischemic myocardium after mannitol. J. Clin. Invest., 51, 2989
Del Maestro, R.F., Thaw, H.H., Bjôrk, J., Planker, M. and Arfors, K.-E. (1980). Free radicals as mediators of tissue injury. In Lewis, D. H. and Del Maestro, R. F. (eds) Acta Physiol. Scand., 492 (suppl.), 43
McCord, J.M. and Fridovich, I. (1969). Superoxide dismutase, an enzymatic function for erythrocuprein. J. Biol. Chem., 244, 6049
Beauchamp, C. and Fridovich, I. (1970). A mechanism for the production of ethylene from methional. The generation of the hydroxyl radical by xanthine oxidase. J. Biol. Chem., 245, 4641
McCord, J.M., Wong, K., Stokes, S.H., Petrone, W.F. and English, D. (1980). Superoxide and inflammation: a mechanism for the anti-inflammatory activity of superoxide dismutase. In Lewis, D.H. and Del Maestro, R.F. (eds) Acta Physiol. Scand., 492 (suppl.), 25
Granger, D.N., Rutili, G. and McCord, J.M. (1982). Superoxide radicals in intestinal ischemia. Gastroenterology (In press)
Guarnieri, C., Flamigni, F. and Carlarera, C.M. (1980). Role of oxygen in the cellular damage induced by re-oxygenation of the hypoxic heart. J. Mol. Cell Cardiol., 12, 797
Berne, R.M. and Rubio, R. (1974). Adenine nucleotide metabolism in the heart. Circ. Res., 35, 109
Saugstad, O. D., Schräder, H. and Aasen, A. O. (1976). Alteration of hypoxanthine level in cerebro-spinal fluid as an indicator of tissue hypoxia. Brain Res., 112, 188
Crowell, J.W., Jones, C.E. and Smith, E.E. (1969). Effect of allopurinol on haemorrhagic shock. Am. J. Physiol., 216, 744
Baker, C. H. (1972). Protection against irreversible haemorrhagic shock by allopurinol. Proc. Soc. Exp. Biol. Med., 141, 694
Parker, J.C. and Smith, E.E. (1972). Effects of xanthine oxidase inhibition in cardiac arrest. Surgery, 71, 339
Pharmacia Symposium No. 1: Free Radicals (1980). Free Radicals in Medicine and Biology, Acta Physiol. Scand., 492 (suppl.)
Ciba Foundation Symposium 65 (new series) (1979). Oxygen Free Radicals and Tissue Damage. ( Amsterdam: Excerpta Medica )
Pryor, W.A. (1976–80). Free Radicals in Biology. (Vols. I-V). (New York: Academic Press)
Sacks, T., Moldow, C.F., Craddock, P.R., Bowers, T.K. and Jacob, S. (1978). Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. J. Clin. Invest., 1161
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Thaw, H.H., Forsberg, J.O., Del Maestro, R.F., Gerdin, B., McKenzie, F.N., Arfors, KE. (1982). A free radical approach to tissue injury. In: Pegg, D.E., Jacobsen, I.A., Halasz, N.A. (eds) Organ Preservation. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6267-8_4
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DOI: https://doi.org/10.1007/978-94-011-6267-8_4
Publisher Name: Springer, Dordrecht
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