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Probiotics in Gut-Bone Signaling

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Understanding the Gut-Bone Signaling Axis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1033))

Abstract

The intestinal environment is linked to an array of conditions and diseases, including osteoporosis. Human and animal studies indicate that probiotics can benefit intestinal health and may provide a useful therapeutic to prevent and/or treat bone loss. Probiotics are defined as live microorganisms that when administered in adequate amounts will confer a health benefit on the host. In this review, we will focus on (1) probiotics (definition, history, nomenclature, types), (2) the effects of probiotics on bone health, and (3) mechanisms of probiotic prevention of bone pathologies.

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Authors and Affiliations

  1. Department of Physiology, Michigan State University, East Lansing, MI, USA

    Jonathan D. Schepper, Regina Irwin, Jun Kang, Kevin Dagenais, Tristan Lemon, Ally Shinouskis & Narayanan Parameswaran

  2. Comparative Medicine and Integrative Biology Program, East Lansing, MI, USA

    Narayanan Parameswaran

  3. Department of Physiology and Department of Radiology, Biomedical Imaging Research Centre, Michigan State University, East Lansing, MI, USA

    Laura R. McCabe

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  1. Jonathan D. Schepper
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  2. Regina Irwin
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  3. Jun Kang
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  4. Kevin Dagenais
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  5. Tristan Lemon
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  6. Ally Shinouskis
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  7. Narayanan Parameswaran
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  8. Laura R. McCabe
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Correspondence to Narayanan Parameswaran or Laura R. McCabe .

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  1. Department of Physiology and Department of Radiology Biomedical Imaging Research Centre, Michigan State University, East Lansing, Michigan, USA

    Laura R. McCabe

  2. Comparative Medicine and Integrative Biology Program, East Lansing, Michigan, USA

    Narayanan Parameswaran

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Schepper, J.D. et al. (2017). Probiotics in Gut-Bone Signaling. In: McCabe, L., Parameswaran, N. (eds) Understanding the Gut-Bone Signaling Axis. Advances in Experimental Medicine and Biology, vol 1033. Springer, Cham. https://doi.org/10.1007/978-3-319-66653-2_11

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