Acute Non-traumatic Weakness

  • Venkataramaiah Sudhir
  • Kamath Sriganesh


A 40-year-old male presented to the emergency with history of severe cramps, abdominal pain, diarrhoea and vomiting. He also complained of blurring of vision, dizziness, generalised weakness and mild difficulty in breathing. On verbalising he was finding it difficult to speak coherently. On examination his pulse rate was 90 beats per minute, BP was 160/90 mmHg and respiratory rate was 18. Neurological examination showed generalised weakness with slowing of reflexes. The attending physician ordered a CT scan, blood investigations and placed the patient under observation. Over 6 h the patient deteriorated further with complete flaccid paralysis and had to be intubated and mechanically ventilated to support respiration. With the preliminary blood investigations normal and the CT brain also showing no significant abnormalities the physician ordered for a toxicology screening. On interviewing the family, the patient was found to have consumed a portion of canned pickles the day before. Botulin toxins were detected in the blood and mouse bioassay also confirmed presence of toxins in the injected serum.


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Copyright information

© The Editor(s) (if applicable) and The Author(s)  2020

Authors and Affiliations

  • Venkataramaiah Sudhir
    • 1
  • Kamath Sriganesh
    • 1
  1. 1.National Institute of Mental Health and NeurosciencesBengaluruIndia

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