Abstract
In the 1930s, cell biologists had surmised that the greatest part of RNA was localized in the cytoplasm and that there was a correlation between the amount of RNA and the protein synthesizing capacity of the cell. In the 1940s, Brachet and Caspersson established unequivocally this correlation with materials as diverse as the root tips of Allium cepa, imaginal disks of Drosophila larvae, secreting pancreatic cells and silk glands from the silkworm and with various methods such as specific dying techniques, specific nucleases and spectrophotometric methods on thin tissue slices.
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Selected References
Davydov II, Wohlgemuth I, Artamonova I, Urlaub H, Tonevisky AG, Rodnina MV (2013) Nat Commun, article number 1387. doi: 10.1038/ncomms2373
Demirci H, Gregory ST, Dahlberg AE, Jogl G (2008) J Biol Chem 283:26548–26556
Guo Z, Noller HF (2012) Proc Natl Acad Sci USA 109:20391–20394
Hershey JWB, Merrick WC (2000) Translational control of gene expression. Cold Spring Harbor Press, Cold Spring Harbor, pp 33–88
Hill WE, Dahlberg A et al (eds) (1990) The ribosome: structure, function and evolution. American Society for Microbiology, Washington, DC, 678 pp
Schachman HK, Pardee AB, Stanier RY (1952) Studies on the macro-molecular organization of microbial cells. Arch Biochem Biophys 38:245–260
Spirin AS (2009) J Biol Chem 284:21103–21119
Waller J-P (1964) J Mol Biol 10:319–336
Mechanistic Aspects of Translation
Peil L, Starosta AL, Lassak J, Atkinson GC, Virumäe K, Spitzer M, Tenson T, Jung K, Remme J, Wilson DN (2013) Proc Natl Acad Sci USA 110:15265–15270
Translocation
Tourigny DS, Fernandez IS, Kelley AC, Ramakrishnan V (2013) Science 340(6140):1235490
Zhou J, Lancaster L, Donohue JP, Noller HF (2013) Science 340(6140):1236086
Ribosome Stalling
Camenares D, Dulebohn DP, Svetlanov A, Wali Karzai A (2013) J Biol Chem 288:30527–30542
Post-translational Modifications of Ribosomal Proteins
Anton BP, Saleh L, Benner JS, Raleigh EA, Kasif S, Roberts RJ (2008) Proc Natl Acad Sci USA 105:1826–1831
Arragain S, Garcia-Serres R, Blondin G, Douki T, Clemancey M, Latour J-M, Forouhar F, Neely H, Montelione GT, Hunt JF, Mulliez E, Fontecave M, Atta M (2010) J Biol Chem 285:5792–5801
Eukaryotic Ribosomes
Dinman JD (2009) J Biol Chem 284:11761–11765
Wool IG (1979) Ann Rev Biochem 48:719–754
Crystallography
Bashan A, Yonath A (2008) Trends Microbiol 16:326–335
Blaha G, Stanley RE, Steitz TA (2009) Science 325:966–970
Moore PB, Steitz TA (2005) Trends Biochem Sci 30:281–283
Ogle JM, Murphy FV, Tarry MJ, Ramakrishnan V (2002) Cell 111:721–732
Schmeing TM, Ramakrishnan V (2009) Nature 461:1234–1242
Yonath A (2002a) Annu Rev Biophys Biomol Struct 31:257–273
Yonath A (2002b) Curr Protein Pept Sci 3:67–78
Protein Folding. Chaperones and Chaperonins
Anfinsen CB (1973) Science 181:223–230
Clare DK, Vasishtan D, Stagg S, Quispe J, Farr GW, Top M, Horwich AL, Saibil HR (2012) Cell 149:113–123
Saibil HR, Fenton WA, Clare DK, Horwich AL (2013) J Mol Biol 425:1476–1487
Wun C-C, Naveen V, Chien C-H, Chang Y-W, Hsiao C-D (2012) J Biol Chem 287:21461–21470
Extraribosomal Functions
Aseev LV, Boni IV (2011) Mol Biol 45:739–750
Singh D, Chang SJ, Lin PH, Averina OV, Kaberdi VR, Lin-Chao S (2009) Proc Natl Acad Sci USA 106:864–869
Vasilyev NN, Kutlubaeva ZS, Ugarov VI, Chetverina HV, Chetverin AB (2013) Nat Commun 4, article number 1781. doi: 10.1038/ncomms2807
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Cohen, G.N. (2014). The Ribosomes, Translation, Chaperones and Chaperonins. In: Microbial Biochemistry. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-8908-0_19
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DOI: https://doi.org/10.1007/978-94-017-8908-0_19
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