Resuspension of Powders and Deposition of Aerosol Particles in the Upper Human Airways

Gradoń, Leon; Sosnowski, Tomasz R.; Moskal, Arkadiusz

doi:10.1007/978-94-017-0267-6_7

Leon Gradoń³,
Tomasz R. Sosnowski³ &
Arkadiusz Moskal³

392 Accesses
2 Citations

Abstract

Aerosols for therapy are produced by ultrasonic nebulizers, pneumatic nebulizers, pressurized metered dose inhalers (pMDI) and dry powder inhalers (DPI). Each method of generation has its own characteristic with specific advantages and disadvantages related to aerosol properties and technical usefulness. A particular system is chosen based on the ease of use for patient and the intent to provide the required therapeutic dose with minimal adverse effects. The most widely used delivery system is the pMDI, which creates therapeutic aerosols from pressurized solution or suspension (Schultz, 1995). Properties of this method of generation are described by J. Pritchard in another chapter of this book.

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Authors and Affiliations

Department of Chemical and Process Engineering, Warsaw University of Technology, Waryńskiego 1, 00-645, Warsaw, Poland
Prof. Leon Gradoń, Dr Tomasz R. Sosnowski & Dr Arkadiusz Moskal

Authors

Prof. Leon Gradoń
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Dr Tomasz R. Sosnowski
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Dr Arkadiusz Moskal
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Editors and Affiliations

University of Technology, Warsaw, Poland
Leon Gradoń
Faculty of Appplied Sciences, Delft University of Technology, Delft, The Netherlands
Jan Marijnissen

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Gradoń, L., Sosnowski, T.R., Moskal, A. (2003). Resuspension of Powders and Deposition of Aerosol Particles in the Upper Human Airways. In: Gradoń, L., Marijnissen, J. (eds) Optimization of Aerosol Drug Delivery. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0267-6_7

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DOI: https://doi.org/10.1007/978-94-017-0267-6_7
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-6436-3
Online ISBN: 978-94-017-0267-6
eBook Packages: Springer Book Archive

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