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Optimization of Aerosol Drug Delivery

  • Leon Gradoń
  • Jan Marijnissen

Table of contents

  1. Front Matter
    Pages I-IX
  2. Bogdan Lesyng, Witold Rudnicki
    Pages 23-48
  3. Kees B. Geerse, Jan C. M. Marijnissen
    Pages 75-90
  4. Leon Gradoń, Tomasz R. Sosnowski, Arkadiusz Moskal
    Pages 123-137
  5. Joachim Heyder, Josef Gebhart, Christa Roth, George A. Ferron
    Pages 139-147
  6. Yung Sung Cheng
    Pages 165-188
  7. Tomasz Ciach, Lidia Diaz, Esther van den IJssel, Jan C. M. Marijnissen
    Pages 189-204
  8. Tomasz R. Sosnowski, Leon Gradoń, Ferry Iskandar, Kikuo Okuyama
    Pages 205-216
  9. P. Zanen
    Pages 243-276
  10. Giuseppe A. Marraro
    Pages 277-293
  11. Leon Gradoń, Jan Marijnissen
    Pages 309-311
  12. Back Matter
    Pages 313-315

About these proceedings

Introduction

Aerosol therapy has significantly improved the treatment of a variety of respiratory diseases. Besides the treatment of respiratory diseases there is currently also a great interest to use the lungs as a portal to introduce drugs for systemic therapy.
The success of therapy with the application of aerosolized medicaments depends on the possibility to deliver the proper amount of drug to the appropriate sites in the respiratory system, thus limiting the side effects to a minimum. Aerosolized delivery of drugs to the lung is optimized if, for a given chemical composition of a medicine, the target of deposition and the required mass of drug to be deposited are precisely defined.
The next step is the specification of the number of respirable particles or droplets, to be generated by appropriate devices. Another very important factor for successful aerosol therapy is the condition of the patient coupled with his or her inhalation technique.

Keywords

Atmen asthma medicine metabolism therapy transport

Editors and affiliations

  • Leon Gradoń
    • 1
  • Jan Marijnissen
    • 2
  1. 1.University of TechnologyWarsawPoland
  2. 2.Faculty of Appplied SciencesDelft University of TechnologyDelftThe Netherlands

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-017-0267-6
  • Copyright Information Springer Science+Business Media B.V. 2003
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-90-481-6436-3
  • Online ISBN 978-94-017-0267-6
  • Buy this book on publisher's site
Industry Sectors
Pharma
Health & Hospitals
Biotechnology