Abstract
Cyclooxygenases (COX)1 catalyze the synthesis of prostaglandins (PGs) from arachidonic acid. There are two isoforms of COX, designated COX-1 and COX-2. COX-1 is expressed constitutively in most tissues and appears to be responsible for housekeeping functions1. In contrast, COX-2 is undetectable in most normal tissues but is induced by growth factors, oncogenes, carcinogens and tumor promoters2–4.
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Dannenberg, A.J., Subbaramaiah, K., Michaluart, P. (2001). Resveratrol, a Novel Inhibitor of Cyclooxygenase-2 Gene Expression. In: Chèze, C., Vercauteren, J., Verpoorte, R. (eds) Polyphenols, Wine and Health. Proceedings of the Phythochemical Society of Europe, vol 48. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-9644-2_3
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DOI: https://doi.org/10.1007/978-94-015-9644-2_3
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