Abstract
As explained in the former chapter, the major disadvantages of absolute coronary flow reserve for clinical decision-making are the variability of normal values, the dependency on hemodynamic loading conditions, and the inability to distinguish the effects of epicardial coronary disease and microvascular disease on coronary blood flow1–5. As a result, there is a wide variation in normal values and a large overlap between normal and pathologic values, i.e. values associated with inducible ischemia or not5–7. Therefore, clinical decision-making based upon absolute coronary flow reserve, remains difficult.
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© 1997 Springer Science+Business Media Dordrecht
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Pijls, N.H.J., De Bruyne, B. (1997). Fractional Flow Reserve. In: Coronary Pressure. Developments in Cardiovascular Medicine, vol 195. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-8834-8_4
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DOI: https://doi.org/10.1007/978-94-015-8834-8_4
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