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Fixation of Tissue for Histochemistry

  • Chapter
Histochemical and Immunohistochemical Techniques

Abstract

The nature of the morphological information sought from any tissue dictates the fixation technique which is used. The first decision to be made is whether fixation will inhibit any subsequent technique to be used, for example, the use of some monoclonal antibodies in which case fixation will be postponed. Sometimes, however, because various techniques have to be used on a single small piece of tissue, a compromise will have to be reached. Wisdom without hindsight is often only a blessing of the gods!

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Hopwood, D. (1991). Fixation of Tissue for Histochemistry. In: Histochemical and Immunohistochemical Techniques. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3094-3_7

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