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Motor neuron degeneration linked to excitatory amino acids: Histological and immunocytochemical approaches

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Amino Acids

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Abstract

Excitatory amino acids are now associated with the pathophysiology of various neurological diseases such as brain ischemia and hypoglycemia, epilepsia [1–3] and some neurodegenerative disorders including Huntington’s disease [4,5] and olivo-ponto-cerebellar atrophy [6]. We have shown recently that two human motoneuron diseases might be reproduced in primates after chronic intoxication with certain uncommon amino acids.

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Author information

Authors and Affiliations

  1. Departments of Neurology, University Hospital, 87 042, Limoges, France

    J. Hugon & J. M. Vallat

  2. Departments of Histology, University Hospital, 87 042, Limoges, France

    J. Hugon & D. Barthe

  3. Center for Occupational Disease Research, Oregon Health Sciences University, Portland, Oregon, USA

    P. S. Spencer

  4. Department of Neurology, University Hospital, 2 rue Alexis Carrel, 87 042, Limoges Cedex, France

    J. Hugon

Authors
  1. J. Hugon
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  2. J. M. Vallat
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  3. P. S. Spencer
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  4. D. Barthe
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Editor information

Editors and Affiliations

  1. Department of Pediatrics, University of Vienna, A-1090, Vienna, Austria

    Gert Lubec

  2. T. H. Morgan School of Biological Sciences and The Graduate Center for Toxicology, University of Kentucky, 40506-0225, Lexington, Kentucky, USA

    Gerald A. Rosenthal

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© 1990 ESCOM Science Publishers B.V.

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Hugon, J., Vallat, J.M., Spencer, P.S., Barthe, D. (1990). Motor neuron degeneration linked to excitatory amino acids: Histological and immunocytochemical approaches. In: Lubec, G., Rosenthal, G.A. (eds) Amino Acids. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2262-7_31

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  • DOI: https://doi.org/10.1007/978-94-011-2262-7_31

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-72199-04-1

  • Online ISBN: 978-94-011-2262-7

  • eBook Packages: Springer Book Archive

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