Abstract
For the interaction of calcium with calcium-binding proteins, which is a prerequisite for the translation of calcium signals into physiological answers, different calcium-binding motifs and thus different families of intracellular calcium-binding proteins have evolved. These families include the C2 domain-containing proteins, the annexins and the EF-hand calcium-binding proteins (Heizmann and Hunziker, 1991). The latter group constitutes a superfamily of proteins with more than 300 members. Within this superfamily, a major discrimination has been made between calcium-buffering and calcium-sensing proteins (Ikura, 1996).
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Braunewell, KH., Reissner, C., Gundefinger, E.D. (2000). Visinin-Like Proteins (VILIPs) — Emerging Role in Cross-Talk between Cellular Signaling Pathways. In: Pochet, R., Donato, R., Haiech, J., Heizmann, C., Gerke, V. (eds) Calcium: The Molecular Basis of Calcium Action in Biology and Medicine. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0688-0_8
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DOI: https://doi.org/10.1007/978-94-010-0688-0_8
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