Abstract
First described in 1898, emphysematous pyelonephritis (EPN) is an acute necrotizing parenchymal and perirenal infection caused by gas forming uropathogens (1-4). Chen et al. (5) identified four factors involved in the pathogenesis of EPN: gas-forming bacteria, high tissue glucose, impaired tissue perfusion and a defective immune response. Diabetics account for 70–90% of all cases (3,6). EPN occurs in nondiabetics in the presence of local factors such as urinary obstruction, tumor embolization or massive kidney infarction (2,7-9).
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Anees, I. (2002). Myth: Surgical intervention and prompt nephrectomy are preferred in emphysematous pyelonephritis. In: Friedman, E.A., Anees, I. (eds) Myths and Shibboleths in Nephrology. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0407-7_17
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DOI: https://doi.org/10.1007/978-94-010-0407-7_17
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