Abstract
Genotoxicity of methane was investigated by assaying mitotic index (MI), chromosomal aberrations (CA), sister chromatid exchanges (SCE) and satellite associations (SA) in short term lymphocyte cultures of 60 male workers occupationally exposed to 56 ppm of methane and 60 matched controls compared with respect to age, sex, smoking and alcohol consumption. Various parameters showed significant increase (p < 0.05). MI (4.61-7.32), CA (0.95-3.81), SCE (3.98-7.22) and SA (8.78-18.12). Smoking and alcohol consumption were found to be confounding factors. Significant effect of period of exposure was also observed.
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© 2002 Narosa Publishing House, New Delhi, India
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Yadav, J.S., Kaushik, V.K. (2002). Genotoxic Investigations on Occupationally Exposed Cattle Yard Workers. In: Sobit, R.C., Obe, G., Athwal, R.S. (eds) Some Aspects of Chromosome Structure and Functions. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0334-6_14
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DOI: https://doi.org/10.1007/978-94-010-0334-6_14
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