Some Aspects of Chromosome Structure and Functions

  • R. C. Sobit
  • G. Obe
  • R. S. Athwal

Table of contents

  1. Front Matter
    Pages i-x
  2. Katsuhiko Kondo, Norikazu Tagashira, Magdy Hussein Abd El-Twab, Yoshikazu Hoshi, Goro Kokubugata, Yoshito Honda et al.
    Pages 27-35
  3. Gian Carlo Manicardi, Mauro Mandrioli, Davide Bizzaro, Umberto Bianchi
    Pages 47-56
  4. G. Kreth, P. Edelmann, Ch. Münkel, J. Langowski, C. Cremer
    Pages 57-71
  5. Bernd Kaina, Klaus Becker, Thomas Grombacher, Günter Obe
    Pages 73-88
  6. V. L. Sharma, R. C. Sobti
    Pages 89-101
  7. Claudio Oliveira, Jonathan M. Wright, Fausto Foresti
    Pages 103-108
  8. O. P. Sharma, N. K. Tripathi, K. K. Sharma
    Pages 109-122
  9. V. L. Sharma, R. C. Sobti
    Pages 123-132
  10. G. Wolf, H. Fender
    Pages 133-148
  11. R. C. Sobti, Jaspreet Kochar, N. Capalash, S. Sharma
    Pages 157-165
  12. R. C. Sobti, Jaspreet Kochar, Neena Capalash, Kamana Parashar, S. Sharma, A. Joshi et al.
    Pages 177-192
  13. R. C. Sobti, S. Sharma, A. K. Janmeja, S. K. Jindal
    Pages 193-205
  14. R. C. Sobti, Adnan Issa AL-Badran, Khadijeh Onsori, S. K. Sharma
    Pages 207-224
  15. R. C. Sobti, Khadijeh Onsory, Adnan Issa AL-Badran, S. K. Sharma, Harsh Mohan
    Pages 225-235
  16. Back Matter
    Pages 237-238

About this book


It was at the end of the 19th century that a Swiss biologist, Karl Nageli first proposed the existence of hereditary organelles that carried information from parent to offspring. Ensuing decades experienced vigorous studies that led to the development of discovery that chromosomes are indeed the carriers of genetic information. Subsequent studies, especially by Morgan and Bridges, established unequivocally the chromosome theory of inheritance. Today, the structure of chromosome is well established. At the physical level, eukaryotic chromosomes are composed of a single, linear, double helix of DNA. The elementary helical structure involves nucleosomes, comprised of histones around which the DNA is wrapped. A hierarchy of higher order of chromosomal architecture may possibly be responsible for the regulation of gene helical structures expression. The localized condensations of DNA constitute chromomeres. Uncoiled structures sometimes extending from chromomeres, which form loops, is the result of discontinuities in the regular coiling of the DNA in the chromosome.


DNA Evolution Telomere chromosome gene expression genes genetics hybridization rDNA

Editors and affiliations

  • R. C. Sobit
    • 1
  • G. Obe
    • 2
  • R. S. Athwal
    • 3
  1. 1.Department of BiotechnologyPanjab UniversityChandigarhIndia
  2. 2.Institute of GeneticsUniversity of EssenEssenGermany
  3. 3.Department of Pathology and Laboratory Medicine Pels Institute for Cancer Research and Molecular BiologyTemple University School of Medicine PhiladelphiaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 2002
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-0-7923-7057-4
  • Online ISBN 978-94-010-0334-6
  • Buy this book on publisher's site
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