Abstract
Intercellular coupling has hitherto been scrutinized nearly in every myocardial structure and at many phylogenetic levels, the human heart being not excepted (Barr, 1969; Bonke, 1973; Bredikis et al., 1976, 1978; Bukauskas et al., 1977a, 1977b; De Mello, 1977; Johnson and Tille, 1961; Sakson et al., 1974; Seyama, 1976; Tanaka and Sasaki, 1966; Weidmann, 1970). The most popular approach in cell to cell coupling studies has been the measurement of passive electrical properties, viz. input resistance and space constant of electrotonic decay. To evaluate these parameters with regard to cell coupling theoretical models are needed which simulate the passive electrical properties and which take into account the actual build up of myocardial tissue as good as possible.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Barr, L.: Electrical transmission between the cells of vertebrate cardiac muscle. In: Comparative Physiology of the Heart: Current Trends. McCann, F.V., ed., Birkenhauser Verlag, Basel and Stuttgart, pp. 102–110, 1969.
Bleeker, W.K., Mackaay, A.J.C., Masson-Pevet, M., Bouman, L.N. and Becker, A.E.: Functional and morphological organization of the rabbit sinus node. Circ. Res., 46: 11–22, 1980.
Bonke, F.I.M.: Electrotonic spread in the sinoatrial node of the rabbit heart. Pfluegers Arch., 339: 17–23, 1973.
Bredikis, J.J., Bukauskas, F.F., Muckus, K.S. and Puodzius, S.S.: Ontogenetic pecularities of the electrical activity in cardiac fibres of human embryo. J. Evol. Biochem. Physiol. (Leningrad), 14: 43–48, 1978.
Bukauskas, F.F., Kukushkin, N.I. and Saxon, M.E.: Model of two-dimensional anisotropic syncitium. Biofizika, 19: 712–716, 1974.
Bukauskas, F.F. and Veteikis, R.P.: Passive electrical properties of AV node region of rabbits heart. Biofizika, 22: 449–504, 1977a.
Bukauskas, F.F., Veteikis, R.P. and Gutman, A.M.: A model for passive three-dimensional anisotropic syncitium as continuous medium. Biofizika, 20: 1083–1086, 1975.
Bukauskas, F.F., Veteikis, R.P., Gutman, A.M. and Mutskus, K.S.: Intercellular electrical coupling in the sinoatrial node of rabbit’s heart. Biofizika, 22: 108–112, 1977b.
Cranefield, P.F. and Greenspan, K.: The rate of oxygen uptake of quiescent cardiac muscle. J. Gen. Physiol., 44: 235–247, 1961.
De Mello, W.C.: Passive electrical properties of the atrioventricular node. Pfluegers Arch., 371: 135–139, 1977.
Hodgkin, A.L. and Rushton, W.A.H.: The electrical constants of a crustacean nerve fibre. Proc. Roy. Soc. London, B133: 444–479, 1946.
Hoffman, B.F.: Atrioventricular conduction in mammalian hearts. Ann. N.Y. Acad. Sci., 127: 105–112, 1965.
Johnson, E.A. and Tille, J.: Investigations of the electrical properties of cardiac muscle fibres with the aid of intracellular double-barrelled electrodes. J. Gen. Physiol., 44: 443–467, 1961.
Kukushkin, N.I., Bukauskas, F.F. and Saxon, M.E.: II. Model of two-dimensional anisotropic syncitium. Biofizika, 19: 888–893, 1974.
Masson-Pevet, M.A.: The fine structure of cardiac pacemaker cells in the sinus node and in tissue culture. (Doct. Thesis), Rodopi, Amsterdam, 1979.
Masuda, M.O. and Paes de Carvalho, A.: Sinoatrial transmission and atrial invasion during normal rhythm in the rabbit heart. Circ. Res., 37: 414–421, 1975.
Matter, A.: A morphometric study on the nexus of rat cardiac muscle. J. Cell Biol., 56: 690–696, 1973.
Pearson, O.H., Hastings, A.B. and Bunting, H.: Metabolism of cardiac muscle: utilization of C14 labelled pyruvate and acetate by heart slices. Amer. J. Physiol., 158: 251–260, 1949.
Purves, R.D.: Current flow and potential in a three-dimensional syncitium. J. Theor. Biol., 60: 147–163, 1976.
Sakson, M.E., Bukauskas, F.F., Kukushkin, N.I. and Nasonova, V.V.: Study of electrotonic distribution on the surface of cardiac structures. Biofizika, 19: 1045–1049, 1974.
Sano, T. and Iida, Y.: Sinoatrial connection and wandering pacemaker. J. Electrocardiol., 1: 147–153, 1968.
Sano, T. and Yamagishi, S.: Spread of excitation from the sinus node. Circ. Res., 16: 423–430, 1965.
Sano, T., Yamagishi, S. and Iida, Y.: Several aspects on the spontaneous activity of the sinus node and its spread. Jap. Circ. J., 30: 134–138, 1966.
Schanne, O.F.: Measurement of cytoplasmic resistivity by means of the glass microelectrodes. In: Glass microelectrodes, Lavallee, M., Schanne, O.F. and Herbert, N.C., eds., Wiley Sons, New York-London-Sydney-Toronto, pp. 299–321, 1969.
Seyama, I.: Characteristics of the rectifying properties of the sino-atrial node cell of the rabbit. J. Physiol. (London), 255: 379–397, 1976.
Smolyaninov, V.V.: Mathematical models of biological tissues (in Russian), Nauka, Moscow, 1980.
Sperelakis, N. and Macdonald, R.L.: Ratio of transverse to longitudinal resistivities of isolated cardiac muscle fiber bundle. J. Electrocardiol., 7: 301–314, 1974.
Strauss, H.C. and Bigger, J.T.: Electrophysiologic properties of the rabbit sinoatrial perinodal fibers. Circ. Res., 31: 490–506, 1972.
Tanaka, I. and Sasaki, Y.: On the electrotonic spread in cardiac muscle of the mouse. J. Gen. Physiol., 49: 1089–1110, 1966.
Trautwein, W. and Uchizono, K.: Electron microscopic and electrophysiologic study of the pacemaker in the sinoatrial node of the rabbit heart. Z. Zellforsch., 61: 96–109, 1963.
Weidmann, S.: Electrical constants of trabecular muscle from mammalian heart. J. Physiol. (London), 210: 1041–1054, 1970.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1982 Martinus Nijhoff Publishers, The Hague
About this chapter
Cite this chapter
Bukauskas, F.F., Gutman, A.M., Kisunas, K.J., Veteikis, R.P. (1982). Electrical Cell Coupling in Rabbit Sino Atrial Node and Atrium Experimental and Theoretical Evaluation. In: Bouman, L.N., Jongsma, H.J. (eds) Cardiac Rate and Rhythm. Developments in Cardiovascular Medicine, vol 17. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7535-4_11
Download citation
DOI: https://doi.org/10.1007/978-94-009-7535-4_11
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-7537-8
Online ISBN: 978-94-009-7535-4
eBook Packages: Springer Book Archive