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Cancer Stem Cells: An Overview

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Methods of Cancer Diagnosis, Therapy, and Prognosis

Part of the book series: Methods of Cancer Diagnosis, Therapy and Prognosis ((HAYAT,volume 7))

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Abstract

A tumor is a proliferation of clones of a single cell that ultimately come to comprise heterogeneous cell populations as proliferation progresses and additional genetic abnormalities arise. Under these conditions, the capacity to sustain tumor formation and growth is restricted to a small population of cells with high tumorigenic ability, called cancer stem cells or tumor-initiating cells. Such cells have been identified in various malignancies, including leukemia, and brain, breast, colon, prostate, pancreas, and head and neck cancers. This chapter reviews the concept of cancer stem cells and recent advances in cancer stem cell research.

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Authors and Affiliations

  1. Department of Pathology, Osaka University School of Medicine, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan

    Eiichi Morii & Katsuyuki Aozasa

Authors
  1. Eiichi Morii
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  2. Katsuyuki Aozasa
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Correspondence to Eiichi Morii .

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Editors and Affiliations

  1. Dept. Biological Sciences, Kean University, Union, 07083, USA

    M. A. Hayat

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Morii, E., Aozasa, K. (2010). Cancer Stem Cells: An Overview. In: Hayat, M. (eds) Methods of Cancer Diagnosis, Therapy, and Prognosis. Methods of Cancer Diagnosis, Therapy and Prognosis, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3186-0_12

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  • DOI: https://doi.org/10.1007/978-90-481-3186-0_12

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-3185-3

  • Online ISBN: 978-90-481-3186-0

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