Methods of Cancer Diagnosis, Therapy, and Prognosis

1. Front Matter

   Pages i-xlvii

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2. General Methods and Overviews

   1. Front Matter

      Pages 1-1

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   2. Role of RNA Interference in Understanding the Molecular Basis of Cancer

      • Jeffrey P. MacKeigan, L. Alex Gaither

      Pages 4-20

   3. Cancer Biomarkers (An Overview)

      • William C. S. Cho

      Pages 21-40

   4. Tumor Angiogenesis in Cancers: Expression of CD105 Marker

      • Osamu Tokunaga, Rahmawati Minhajat, Daisuke Mori

      Pages 41-50

   5. Spindle Cell Oncocytoma of the Adenohypophysis: Integrated Clinicopathologic Diagnosis by Imaging, Histology, and Immunohistochemistry

      • Istvan Vajtai, Rahel Sahli

      Pages 51-57

   6. Disseminated Carcinoma of Unknown Primary Site: Detection with F-Fluorodeoxyglucose-Positron Emission Tomography

      • Pascal Sève, John R. Mackey

      Pages 59-71

   7. Unknown Lymphadenopathy: Diagnosing Using an Endoscopic Ultrasound-Guided Fine-Needle Aspiration Biopsy

      • Ichiro Yasuda

      Pages 73-78

   8. Pretargeted Radioimmunotherapy in Cancer: An Overview

      • Stefano Papi, Chiara Grana Grana, Mirco Bartolomei, Laura Ravasi, Marta Cremonesi, Mahila Ferrari et al.

      Pages 80-98

   9. Chemotherapy-Induced Neurotoxicity

      • Susanna B. Park, Matthew C. Kiernan

      Pages 99-119

   10. Multidrug Resistance

       • Ernesto Yagüe, Selina Raguz

       Pages 121-133

   11. Role of Antibodies in Cancer Treatment (An Overview)

       • Huguette Albrecht

       Pages 135-152

   12. Incorporating Pharmacogenomics into Cancer Therapy

       • Wooin Lee, A. Craig Lockhart

       Pages 153-172

   13. Cancer Stem Cells: An Overview

       • Eiichi Morii, Katsuyuki Aozasa

       Pages 173-181

   14. Translating In Vitro Cell Lines Result into Clinical Practice

       • Jai Prakash Mehta, Lorraine O’Driscoll, Niall Barron, Martin Clynes, Padraig Doolan

       Pages 183-191

   15. Classification of Cancer Stage Using Patient’s Immune System

       • P. Pellegrini, I. Contasta, A. M. Berghella, T. Del Beato, D. Adorno

       Pages 194-213

   16. Late Relapse of Germ Cell Malignancies: Incidence, Management, and Prognosis

       • Jan Oldenburg, Sophie D. Fossa

       Pages 215-226

3. Head and Neck Cancer

   1. Front Matter

      Pages 228-228

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   2. Head and Neck Squamous Cell Carcinoma: Therapy with Fusaric Acid/Paclitaxel

      • Brendan C. Stack Jr., Brett Clarke, Joshua McElderry, Yeumeng Dai, Jian-Hui Ye

      Pages 229-235

   3. Early Stage Oral Squamous Cell Carcinoma: Use of Signal Transducer and Activator of Transcription 3 as a Risk Factor for Poor Diagnosis

      • N. G. Shah, T. I. Trivedi

      Pages 237-253

There are more than 100 types of cancers In Part II, head and neck cancer is d- affecting all parts of the human body. cussed. The global number of annual new More than 11 million people are diagnosed cases of this malignancy is ~500,000. These with cancer every year, and it is estimated malignancies include oral squamous cell that there will be 16 million new cases by carcinoma, salivary gland tumors, tons- the year 2020. In 2005, 7. 6 million peo- lar cancer, tongue cancer, nasopharyngeal ple died of cancer, that is, 13% of the 58 carcinoma, and retinoblastoma, which are million deaths worldwide. It is estimated detailed. In Part III, diagnosis, therapy, and that 9 million people will die from can- prognosis of thyroid carcinoma are d- cer worldwide in 2015 and 11. 4 million cussed. The global number of new cases of will die in 2030. More than 70% of all thyroid cancer is ~141,000, and the number cancer deaths occur in low and middle of worldwide thyroid mortalities is ~35,375. income countries. These statistics underlie The number of new cases of this cancer in the fact that cancer is the deadliest of all the United States is ~33,550. Molecular human diseases. The enormity of the glo- genetics of thyroid cancer, gene expr- bal healthcare costs as a result of cancer sion markers for diagnosis, papillary t- cannot be overemphasized.

• Oncology
• Staging
• Tumor
• angiogenesis
• biopsy
• carcinoma
• classification
• diagnosis
• endoscopy
• imaging
• positron emission tomography
• ultrasound
• surgical oncology
• Radiaton Oncology

• Dept. Biological Sciences, Kean University, Union, USA

  M. A. Hayat

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