Abstract
Cutaneous lesions are well-recognized extraintestinal manifestations of inflammatory bowel disease (IBD), specifically. Crohn’s disease (CD) and ulcerative colitis (UC). These extraintestinal manifestations, associated with intestinal symptoms, contribute to the impaired quality of life of patients with CD. During the course of the disease, a great variety of cutaneous lesions may develop, many of which are secondary to granulomatous cutaneous disease, reactive skin eruptions, undernourishment, pharmacological treatment, and other associated conditions [1]. The occurrence of these manifestations varies widely but the mean incidence is around 10% [2]. The cutaneous abnormalities that accompany IBD can be viewed as a spectrum of changes resulting from leukocyte migration to different sites of the skin. Diagnosis of the cutaneous manifestations of CD is made on clinical grounds, based on their characteristics features, and the exclusion of other specific skin disorders; biopsy is rarely appropriate or necessary [3]. Whether the cutaneous manifestations can be considered as real extraintestinal patterns of CD or simply represent associations between different autoimmune diseases is still not clear.
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Alessandroni, L., Scotti, A. (2010). Cutaneous Manifestations. In: Tersigni, R., Prantera, C. (eds) Crohn’s Disease. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-1472-5_19
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DOI: https://doi.org/10.1007/978-88-470-1472-5_19
Publisher Name: Springer, Milano
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