Physical Inactivity is the Main Cause of the Metabolic Syndrome

  • Pierpaolo De Feo
  • Chiara Di Loreto
  • Anna Ranchelli
  • Cristina Fatone
  • Paola Lucidi
  • Fausto Santeusanio


The metabolic syndrome is characterized by the coexistence of visceral adiposity, impaired fasting glucose or overt diabetes mellitus, reduced HDL cholesterol, and increased blood pressure and triglycerides. In Western and developing countries the prevalence of the metabolic syndrome is rising because the explosion of the twin epidemics: obesity and diabetes [1 5]. Visceral adiposity plays a key role in the subsequent manifestation of diabetes and of the full metabolic syndrome. The present article sustains the hypothesis that obesity, diabetes, and the metabolic syndrome are increasing mainly because people no longer need to be physically active in their daily lives [1 5].


Metabolic Syndrome Physical Fitness Physical Inactivity Diabetic Subject Average Energy Expenditure 
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Copyright information

© Springer 2007

Authors and Affiliations

  • Pierpaolo De Feo
    • 1
  • Chiara Di Loreto
    • 1
  • Anna Ranchelli
    • 1
  • Cristina Fatone
    • 1
  • Paola Lucidi
    • 1
  • Fausto Santeusanio
  1. 1.Department of Internal Medicine Section Internal Medicine Endocrine and Metabolic SciencesUniversity of PerugiaPerugiaItaly

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