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Rapid Synthesis of Oligosaccharides: Resin Capture-Release Strategy

  • Yukishige Ito
  • Shinya Hanashima

Abstract

A number of methodologies for efficient and selective O-glycoside bond formation have been successfully developed. Using these methods, syntheses of complex oligosaccharides have been achieved. However, chemical synthesis of glycoprotein-derived oligosaccharide or their derivative is technically demanding and highly time-consuming. In order that synthetic chemistry is going to function as the driving force in glycobiology, speeding up and automation are the key issues (Seeberger and Haase 2000).

Keywords

Polymer Support Combine Organic Layer Release Strategy Ethyl Chloroformate Oligosaccharide Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer 2008

Authors and Affiliations

  • Yukishige Ito
    • 1
    • 2
  • Shinya Hanashima
    • 1
    • 2
  1. 1.RIKEN (The Institute of Physical and Chemical Research)Wako, SaitamaJapan
  2. 2.CREST, JSTKawaguchi, saitamaJapan

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