Oligosaccharide Synthesis Based on Combinatorial Chemistry and Labo Automation
Combinatorial chemistry is an effective method not only for the rapid assembly of small molecule libraries but also for the optimization of reaction conditions. Labo automation permits laborious and routine manipulations to be minimized. In this report, we describe the application of combinatorial chemistry and labo automation to the synthesis of oligosaccharide libraries.
KeywordsCombinatorial Chemistry Benzyl Ether Glycosyl Donor Hydrazine Monohydrate Oligosaccharide Synthesis
Unable to display preview. Download preview PDF.
- Tanaka H, Matoba N, Tsukamoto H, Takimoto H, Yamada H, Takahashi T (2005a) Automated parallel synthesis of a protected oligosaccharide library based upon the structure of dimeric Lewis X by onepot sequential glycosylation. Synlett 824–828Google Scholar