Stationary Solid-Phase Reaction (SSPR) for Oligosaccharide Synthesis

  • Takuro Ako
  • Osamu Kanie


Synthetic methods to access oligosaccharide structures are extremely important to provide bio-probes for the functional analysis. Furthermore, a combinatorial oligosaccharide library is potentially important in terms of diagnoses and providing potential seeds for new pharmaceuticals.


Focus Area Synthetic Method Yielding Reaction Acceptor Solution Temperature Increment 
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  1. Ako T, Daikoku S, Ohtsuka I, Kato R, Kanie O (2006) A method of orthogonal oligosaccharide synthesis leading to combinatorial library based on stationary solid-phase reaction. Chem Asian J 1:798–813PubMedCrossRefGoogle Scholar
  2. Kanie O, Ohtsuka I, Ako T, Daikoku S, Kanie Y, Kato R (2006) Orthogonal glycosylation reactions on solid-phase and the synthesis of a library consisting of a complete set of fucosyl galactose isomers. Angew Chem Int Ed 45:3851–3854CrossRefGoogle Scholar

Copyright information

© Springer 2008

Authors and Affiliations

  • Takuro Ako
    • 1
  • Osamu Kanie
    • 1
  1. 1.Mitsubishi Kagaku Institute of Life Sciences (MITILS)Machida, TokyoJapan

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