Biosynthesis of Keratan Sulfate

  • Akira Seko
  • Katsuko Yamashita


Keratan sulfate (KS) is a poly-sulfated glycosaminoglycan with a poly-N-acetyllactosamine linear chain structure. KS is a rich component in cornea, and is also present in cartilage and brain. In cornea, KS plays important roles in maintaining water content and developing collagen matrix. Recent studies have demonstrated its association with Alzheimer’s disease and arthritis.


Hyaluronic Acid Chondroitin Sulfate Keratan Sulfate Sulfate Glycosaminoglycan Corneal Dystrophy 
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Copyright information

© Springer 2008

Authors and Affiliations

  • Akira Seko
    • 1
  • Katsuko Yamashita
  1. 1.Innovative Research InitiativesTokyo Institute of TechnologyYokohamaJapan

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