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Biosynthesis of Keratan Sulfate

  • Akira Seko
  • Katsuko Yamashita

Abstract

Keratan sulfate (KS) is a poly-sulfated glycosaminoglycan with a poly-N-acetyllactosamine linear chain structure. KS is a rich component in cornea, and is also present in cartilage and brain. In cornea, KS plays important roles in maintaining water content and developing collagen matrix. Recent studies have demonstrated its association with Alzheimer’s disease and arthritis.

Keywords

Hyaluronic Acid Chondroitin Sulfate Keratan Sulfate Sulfate Glycosaminoglycan Corneal Dystrophy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer 2008

Authors and Affiliations

  • Akira Seko
    • 1
  • Katsuko Yamashita
  1. 1.Innovative Research InitiativesTokyo Institute of TechnologyYokohamaJapan

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