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Microvascular Leukocyte Plugging in Evolving Brain Infarction in Humans

  • J. Ogata
  • J. Masuda
  • C. Yutani
  • K. Minematsu
  • T. Yamaguchi
Conference paper

Abstract

Animal experiments on “no-reflow” early after cerebral ischemia and reperfusion suggest significant participation of leukocytes in postischemic neuronal damage [1]. In humans, however, leukocyte responses to arterial occlusion with or without reperfusion are not fully known. Therefore, we examined the histopathological specimens of the areas of early ischemia of the brain in autopsy cases.

Keywords

Cerebral Ischemia Brain Death Focal Cerebral Ischemia Cortical Gray Matter Postcapillary Venule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    del Zoppo GJ, Schmid-Schönbein GW, Mori E, Copeland BR, Chang CM (1991) Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke 22: 1276–1283PubMedCrossRefGoogle Scholar
  2. 2.
    Ogata J, Yutani C, Imakita M, Ishibashi-Ueda H, Saku Y, Minematsu K, Sawada T, Yamaguchi T (1989) Hemorrhagic infarct of the brain without a reopening of the occluded arteries in cardioembolic stroke. Stroke 20: 876–883PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1995

Authors and Affiliations

  • J. Ogata
    • 1
  • J. Masuda
    • 1
  • C. Yutani
    • 2
  • K. Minematsu
    • 3
  • T. Yamaguchi
    • 3
  1. 1.Research InstituteNational Cardiovascular CenterSuita, Osaka, 565Japan
  2. 2.Department of PathologyNational Cardiovascular CenterSuita, Osaka, 565Japan
  3. 3.Cerebrovascular Division, Department of MedicineNational Cardiovascular CenterSuita, Osaka, 565Japan

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