Abstract
Some muscle disorders are known to be associated with malignant hyperthermia (MH), including King-Denborough syndrome and central-core disease (CCD), and occasionally Duchenne muscular dystrophy and myotonias. Among them, mitochondrial myopathies (MM) have been occasionally reported [1,2]. In a recent publication by Harriman concerning 1400 patients investigated by the Leeds MH unit (R. Ellis), no histological sign of MM such as ragged red fibers or negative staining of cytochrome c oxidase was described [3]. Our results are in agreement with those of Harriman: whatever the in vitro contracture test results, pathological findings were heterogenous [4]. Therefore, our observation of mitochondrial abnormalities in 25 of 234 patients (10.6%) led us to investigate these patients further by additional adequate tests.
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© 1996 Springer-Verlag Tokyo
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Kozak-Ribbens, G. (1996). Mitochondrial Disorders in Malignant Hyperthermia. In: Morio, M., Kikuchi, H., Yuge, O. (eds) Malignant Hyperthermia. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68346-9_18
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DOI: https://doi.org/10.1007/978-4-431-68346-9_18
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68348-3
Online ISBN: 978-4-431-68346-9
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