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Caffeine Contracture of the Skinned Muscle Fiber in Malignant Hyperthermia and Neuromuscular Diseases

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Malignant Hyperthermia

Abstract

Caffeine contracture of skinned muscle fiber was analyzed in subjects who had recovered from malignant hyperthermia (MH) and in patients with other neuromuscular diseases. In several muscle specimens, the calcium-induced (Ca-induced) Ca release (CICR) was also studied and compared to the caffeine contracture. The caffeine contracture test was very sensitive in detecting abnormalities, but it seemed less specific for diagnosis of true MH.

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© 1996 Springer-Verlag Tokyo

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Takagi, A., Araki, M., Kojima, S., Ida, M., Watanabe, T. (1996). Caffeine Contracture of the Skinned Muscle Fiber in Malignant Hyperthermia and Neuromuscular Diseases. In: Morio, M., Kikuchi, H., Yuge, O. (eds) Malignant Hyperthermia. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68346-9_10

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  • DOI: https://doi.org/10.1007/978-4-431-68346-9_10

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68348-3

  • Online ISBN: 978-4-431-68346-9

  • eBook Packages: Springer Book Archive

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