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Hereditary Non-polyposis Colorectal Cancer: The University of Texas MD Anderson Cancer Center Experience

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Hereditary Colorectal Cancer

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Abstract

The UT M. D. Anderson Cancer Center recently initiated a registry for Hereditary Non-polyposis Colorectal Cancer (HNPCC). Modelled after the Creighton program, our interests include early detection and clinical management, intermediate laboratory markers, and chemoprevention. Kindreds registered to date have the usual features of HNPCC. Mucosal markers (tritiated thymidine and bromodeoxyuridine labelling) have varied considerable amongst high-risk subjects studied. A multi-centered prospective screening trial, with further evaluation of intermediate markers and chemoprevention strategies is proposed.

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Authors
  1. Patrick M. Lynch
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  2. Rodger J. Winn
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  3. Michael J. Wargovich
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  4. Bernard Levin
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Editor information

Editors and Affiliations

  1. Second Department of Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663, Japan

    Joji Utsunomiya M. D. (Professor and Chairman) (Professor and Chairman)

  2. Department of Preventive Medicine, Creighton University School of Medicine, Hereditary Cancer Center, California at 24th Street, Omaha, NE, 68178, USA

    Henry T. Lynch M. D. (Professor and Chairman) (Professor and Chairman)

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© 1990 Springer Japan

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Lynch, P.M., Winn, R.J., Wargovich, M.J., Levin, B. (1990). Hereditary Non-polyposis Colorectal Cancer: The University of Texas MD Anderson Cancer Center Experience. In: Utsunomiya, J., Lynch, H.T. (eds) Hereditary Colorectal Cancer. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68337-7_29

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  • DOI: https://doi.org/10.1007/978-4-431-68337-7_29

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68339-1

  • Online ISBN: 978-4-431-68337-7

  • eBook Packages: Springer Book Archive

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