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Molecular Biology

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Atlas of Exocrine Pancreatic Tumors

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Abstract

Morphological studies of pancreatic cancers do not provide sufficient information to predict their biological behavior. The study of genetic abnormalities in pancreatic cancers may open new paths for understanding the etiology and pathogenesis of the disease, and may help in establishing markers for diagnosis and prognosis. There is increasing evidence that it is the accumulation of different genetic abnormalities, rather than a single gene defect, that underlies the multistage processes of tumorigenesis and progression of malignancy [1]. Growth factors and their receptors, tumor suppressor genes, and oncogenes have received considerable attention and seem to be promising in assessing of malignant potential [2].

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Author information

Authors and Affiliations

  1. The Eppley Institute for Research in Cancer; Department of Pathology and Microbiology, University of Nebraska Medical Center, 68198-6805, Omaha, NE, USA

    Parviz M. Pour M.D.

  2. Department of Oncological Pathology, Cancer Center, Nara Medical College, Kashihara, Nara, 634, Japan

    Yoichi Konishi M.D.

  3. Department of Pathology, Academy Hospital Jette, Free University of Brussels, 1090, Brussels, Belgium

    Günter Klöppel M.D.

  4. Department of Pathology, Dartmouth Medical School, 03756, Hanover, NH, USA

    Daniel S. Longnecker M.D.

Authors
  1. Parviz M. Pour M.D.
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  2. Yoichi Konishi M.D.
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  3. Günter Klöppel M.D.
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  4. Daniel S. Longnecker M.D.
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Editor information

Editors and Affiliations

  1. The Eppley Institute for Research in Cancer; Department of Pathology and Microbiology, University of Nebraska Medical Center, 68198-6805, Omaha, NE, USA

    Parviz M. Pour M.D.

  2. Department of Oncological Pathology, Cancer Center, Nara Medical College, Kashihara, Nara, 634, Japan

    Yoichi Konishi M.D.

  3. Department of Pathology, Academy Hospital Jette, Free University of Brussels, 1090, Brussels, Belgium

    Günter Klöppel M.D.

  4. Department of Pathology, Dartmouth Medical School, 03756, Hanover, NH, USA

    Daniel S. Longnecker M.D.

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© 1994 Springer-Verlag Tokyo

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Pour, P.M., Konishi, Y., Klöppel, G., Longnecker, D.S. (1994). Molecular Biology. In: Pour, P.M., Konishi, Y., Klöppel, G., Longnecker, D.S. (eds) Atlas of Exocrine Pancreatic Tumors. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68311-7_20

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  • DOI: https://doi.org/10.1007/978-4-431-68311-7_20

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68313-1

  • Online ISBN: 978-4-431-68311-7

  • eBook Packages: Springer Book Archive

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