About this book
Introduction
The classification of tumors is important for understanding tumor histogenesis, for predicting prognosis, for differential diagnosis, and for recommending appropriate therapy. Since 1836, when pancreatic cancer was first described, progress has been made in pancreatic cancer morphology, and a number of classifications have been proposed. All of these classifications are mainly based on morphological characteristics. Some are too detailed to be of practical use while others are more pragmatic. Some of the inherent problems in the previous classifications included difficulties in obtaining an adequate number of pan creatic tumors for examination and insufficient clinical data and follow-up. With the increasing incidence of pancreatic cancer in many parts of the world during the past six decades, and with the availability of more tumors to patho logists, advances have been made in pancreatic tumor studies. Classifications by Cubilla and Fitzgerald and by Kloppel, which are generally similar, mostly considered prominent morphological features and their histogenesis. These pathology-oriented classifications, although complete, were not practical from the standpoint of clinicians concerned with the prognosis of individual tumors.
Keywords
Staging cancer carcinoma cell classification differential diagnosis gastroenterology histopathology molecular biology oncology pancreas pancreatic cancer pathology tissue tumor
Editors and affiliations
- Parviz M. Pour
- Yoichi Konishi
- Günter Klöppel
- Daniel S. Longnecker
- 1.The Eppley Institute for Research in Cancer; Department of Pathology and MicrobiologyUniversity of Nebraska Medical CenterOmahaUSA
- 2.Department of Oncological Pathology, Cancer CenterNara Medical CollegeKashihara, NaraJapan
- 3.Department of Pathology, Academy Hospital JetteFree University of BrusselsBrusselsBelgium
- 4.Department of PathologyDartmouth Medical SchoolHanoverUSA
Bibliographic information