Anaplastic (Undifferentiated) Carcinoma

  • Parviz M. Pour
  • Yoichi Konishi
  • Günter Klöppel
  • Daniel S. Longnecker


Giant Cell Multinucleated Giant Cell Giant Cell Tumour Giant Cell Tumor Anaplastic Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Sommers SL, Meissner WA (1954) Unusual carcinoma of the pancreas. Arch Pathol 58: 101–111Google Scholar
  2. 2.
    Gudjonsson B (1987) Cancer of the pancreas. 50 years of surgery. Cancer 60: 2284–2303PubMedCrossRefGoogle Scholar
  3. 3.
    Cubilla AL, Fitzgerald PJ (1984) Giant cell carcinoma (osteoclastoid type). In: Firminger HI (ed) Atlas of tumor pathology, Series 2, Fascicle 19. Washington, DC, Armed Forces Institute of Pathology, pp 162–167Google Scholar
  4. 4.
    Combs SG, Hidvegi DF, Ma Y, Rosen ST, Radosevich JA (1988) Pleomorphic carcinoma of the pancreas with osteoclast-like giant cells expressing an epithelial-associated antigen detected by monoclonal antibody 44–3A6. Diagn Cytopathol 4: 316322Google Scholar
  5. 5.
    Gatteschi B, Saccomanno S, Bartoli FG, Salvi S, Pugliese V (to be published) Mixed giant cell tumor of the pancreas. A case report with light microscopy and immunohistochemical features. Int J PancreatolGoogle Scholar
  6. 6.
    Nojima T, Nakamura F, Ishikura M, Inoue K, Nagashiwa K, Kato H (1993) Pleomorphic carcinoma of the pancreas with osteoclast-like giant cells. Int J Pancreatol 14: 275–281PubMedGoogle Scholar
  7. 7.
    Lewandrowski KB, Weston L, Dickerson Rattner DW, Compton CC (1990) Giant cell tumor of the pancreas of mixed osteoclastic and pleomorphic cell type: evidence for a histogenetic relationship and mesenchymal differentiation. Hum Pathol 21: 11841187Google Scholar
  8. 8.
    Silverman JF, Dabbs DJ, Finley JK, Geisinger KR (1988) Fine-needle aspiration biopsy of pleomorphic (giant cell) carcinoma of the pancreas. Cytologic, immunocytochemical, and ultrastructural findings. Am J Clin Pathol 89: 714–720Google Scholar
  9. 9.
    Pinto MM, Monteiro NL, Tizol DM (1986) Fine needle aspiration of pleomorphic giant-cell carcinoma of the pancreas. Acta Cytol 30: 430–434PubMedGoogle Scholar
  10. 10.
    Jeffrey I, Crow J, Ellis BW (1983) Osteoclast-type giant cell tumour of the pancreas. J Clin Path 36: 1165–1170PubMedCrossRefGoogle Scholar
  11. 11.
    Fischer H-P, Altmannsberger M, Kracht J (1988) Osteoclast-type giant cell tumor of the pancreas. Virch Arch 412: 247–253CrossRefGoogle Scholar
  12. 12.
    Kay S, Harrison JM (1968) Unusual pleomorphic carcinoma of the pancreas featuring production of osteoid. Cancer 23: 1158–1162CrossRefGoogle Scholar
  13. 13.
    Rosai J (1968) Carcinoma of pancreas simulating giant cell tumor of bone: electron microscopic evidence of its acinar cell origin. Cancer 22: 333–344PubMedCrossRefGoogle Scholar
  14. 14.
    Robinson L, Damjenov I, Brezind P (1977) Multinucleated giant cell neoplasm of pancreas. Light and electron microscopy features. Arch Pathol Lab Med 101: 590–593Google Scholar
  15. 15.
    Tschang T, Garza-Garza R, Kissane JM (1977) Pleomorphic carcinoma of the pancreas. An analysis of 15 cases. Cancer 39: 2114–2126PubMedCrossRefGoogle Scholar
  16. 16.
    Alguacil-Garcia A, Weiland LH (1977) The histologic spectrum, prognosis and histogenesis of the sarcomatoid carcinoma of the pancreas. Cancer 39: 1181–1189PubMedCrossRefGoogle Scholar
  17. 17.
    Jalloh S (1983) Giant cell tumour (osteoclastoma) of the pancreas, an epithelial tumour probably of pancreatic acinar origin. J Clin Pathol 36: 1165–1170CrossRefGoogle Scholar
  18. 18.
    Manci EA, Gardner LL, Pollock WJ, Dowling EA (1985) Osteoclastic giant cell tumor of the pancreas. Aspiration cytology, light microscopy and ultrastructure with review of the literature. Diagn Cytopathol 1: 105–110Google Scholar
  19. 19.
    Cubilla AL, Fitzgerald PJ (1979) Cancer of the pancreas (nonendocrine): a suggested morphological 23. classification. Semin Oncol 6: 285–297PubMedGoogle Scholar
  20. 20.
    Trepeta RW, Mathur B, Lagin S, Livolsi V (1981) Giant cell tumor (“osteoclastoma”) of the pancreas: 24. a tumor of epithelial origin. Cancer 48: 20262–2028CrossRefGoogle Scholar
  21. 21.
    Posen JA, Path FF (1981) Giant cell tumour of the pancreas of the osteoclastic type associated with a mucous secreting cystoadenocarcinoma. Hum Pathol 25. 12: 944–947CrossRefGoogle Scholar
  22. 22.
    Berendt RC, Shnitka TK, Wiens E, Manickavel V, Jewel LD (1987) The osteoclast-type giant cell tumor of the pancreas. Arch Pathol Lab Med 111: 43–48PubMedGoogle Scholar
  23. 23.
    Fisher HP, Ahmannsberger M, Cracht J (1988) Osteoclast-type giant cell tumour of the pancreas. Virch Arch (A) 412: 247–253CrossRefGoogle Scholar
  24. 24.
    Goldberg RD, Michelassi F, Montag AG (1991) Ostoclast-like giant cell tumor of the pancreas: immunophenotypic similarity to giant cell tumor of bone. Hum Pathol 6: 618–622CrossRefGoogle Scholar
  25. 25.
    Pour PM (1985) Induction of unusual pancreatic neoplasms with morphologic similarity to human tumors and evidence for their ductal/ductular cell origin. Cancer 55: 2411–2416PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1994

Authors and Affiliations

  • Parviz M. Pour
    • 1
  • Yoichi Konishi
    • 2
  • Günter Klöppel
    • 3
  • Daniel S. Longnecker
    • 4
  1. 1.The Eppley Institute for Research in Cancer; Department of Pathology and MicrobiologyUniversity of Nebraska Medical CenterOmahaUSA
  2. 2.Department of Oncological Pathology, Cancer CenterNara Medical CollegeKashihara, NaraJapan
  3. 3.Department of Pathology, Academy Hospital JetteFree University of BrusselsBrusselsBelgium
  4. 4.Department of PathologyDartmouth Medical SchoolHanoverUSA

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