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Discrepancy of Recovery Times Related to Potency Between Atracurium and Mivacurium Simultaneously Administered into the Isolated Forearms

  • Sung-Yell Kim
  • Kyung-Ho Hwang
  • Si-Young Ok
  • Soon-Im Kim
  • Sun-Chong Kim
  • Wook Park
Conference paper

Abstract

The recovery from potent non-depolarizing muscle relaxants is slower than that from the less potent agents(1). However the recovery time for mivacurium(MIV), which is more potent than atracurium(ATR), is faster than that of ATR after systemic administration(2). This discrepancy may be due to the rapid hydrolysis by plasma cholinesterase in MIV and more persistent plasma level in ATR. In an attempt to confirm this, we have compared the recovery times following simultaneous administration of equipotent doses of ATR and MIV into the two isolated forearms of a human volunteer(3).

Keywords

Recovery Time Systemic Administration Ulnar Nerve Plasma Cholinesterase Rapid Hydrolysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Law Min JC, Bekavac I, Glavinonic MI et al. Anesthesiology 1992;77:351–356.CrossRefGoogle Scholar
  2. 2.
    Savarese JJ, Ali HH, Basta SJ et al. Anesthesiology 1988;68:723–732.PubMedCrossRefGoogle Scholar
  3. 3.
    Feldman SA, Tyrrell MF. Proceeding Royal of Medicine 1970;63:692–696.Google Scholar

Copyright information

© Springer Japan 1995

Authors and Affiliations

  • Sung-Yell Kim
    • 1
  • Kyung-Ho Hwang
    • 1
  • Si-Young Ok
    • 1
  • Soon-Im Kim
    • 1
  • Sun-Chong Kim
    • 1
  • Wook Park
    • 1
  1. 1.Department of AnesthesiologySoon Chun Hyang University, School of Medicine SeoulKorea

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