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Comparison of the Neuromuscular Effects of SZ1676 and Vecuronium in Guinea-Pig

  • K. Tomizawa
  • J. Takeda
  • J. Oshida
  • K. Watanabe
  • K. Fukushima
Conference paper

Abstract

A new nondepolarizing, steroid type muscle relaxant (MR), SZ1676 (1-[3 α, 17 β-Bis(acetyloxy)-2 β -(1.4-dioxa-8-azaspiro[4.5]dec-8-yl)-5 α-androstan-16 β -yl]-1-(2propenyl)pyrrolidinium bromide) has been introduced recently 1,2). In this study, the pharmaco-dynamic effects of SZ1676 and vecuronium (Vb) have been compared in vitro of guinea-pig.

Keywords

Recovery Time Muscle Relaxant Onset Time Phrenic Nerve Organ Bath 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1).
    Jap J Clin Pharmacol 1993, 117.Google Scholar
  2. 2).
    Anesth Analg 1994,78:S438Google Scholar

Copyright information

© Springer Japan 1995

Authors and Affiliations

  • K. Tomizawa
    • 1
  • J. Takeda
    • 1
  • J. Oshida
    • 1
  • K. Watanabe
    • 1
  • K. Fukushima
    • 1
  1. 1.Department of AnesthesiologyKeio University School of MedicineShinjuku-ku, Tokyo, 160Japan

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