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Comparison of the Neuromuscular Effects of SZ1676 and Vecuronium in Guinea-Pig

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Muscle Relaxants

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Abstract

A new nondepolarizing, steroid type muscle relaxant (MR), SZ1676 (1-[3 α, 17 β-Bis(acetyloxy)-2 β -(1.4-dioxa-8-azaspiro[4.5]dec-8-yl)-5 α-androstan-16 β -yl]-1-(2propenyl)pyrrolidinium bromide) has been introduced recently 1,2). In this study, the pharmaco-dynamic effects of SZ1676 and vecuronium (Vb) have been compared in vitro of guinea-pig.

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References

  1. Jap J Clin Pharmacol 1993, 117.

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  2. Anesth Analg 1994,78:S438

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Author information

Authors and Affiliations

  1. Department of Anesthesiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160, Japan

    K. Tomizawa, J. Takeda, J. Oshida, K. Watanabe & K. Fukushima

Authors
  1. K. Tomizawa
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  2. J. Takeda
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  3. J. Oshida
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  4. K. Watanabe
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  5. K. Fukushima
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Editor information

Editors and Affiliations

  1. Department of Anesthesiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160, Japan

    Kazuaki Fukushima M.D., Ph.D (Professor and Chairman) & Ryoichi Ochiai M.D., Ph.D (Professor and Chairman) & 

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© 1995 Springer Japan

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Tomizawa, K., Takeda, J., Oshida, J., Watanabe, K., Fukushima, K. (1995). Comparison of the Neuromuscular Effects of SZ1676 and Vecuronium in Guinea-Pig. In: Fukushima, K., Ochiai, R. (eds) Muscle Relaxants. Springer, Tokyo. https://doi.org/10.1007/978-4-431-66896-1_82

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  • DOI: https://doi.org/10.1007/978-4-431-66896-1_82

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-66898-5

  • Online ISBN: 978-4-431-66896-1

  • eBook Packages: Springer Book Archive

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