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Neuromuscular Recovery During Washout of Desflurane vs. Isoflurane

  • D. M. Fisher
  • P. S. Hart
  • P. M. C. Wright
  • M. Lau
  • R. Brown
  • M. Sharma
Conference paper

Abstract

Although potentiation of muscle relaxants by inhaled anesthetics is desirable (it reduces the total dose of muscle relaxant and, presumably, the plasma concentration of the relaxant), recent investigations suggest that potentiation persists beyond washout of the inhaled anesthetic (1). Because desflurane exits rapidly from lung (and possibly from muscle), we evaluated neuromuscular function during washout of inhaled anesthetics during steady state vecuronium infusion. To minimize the effect of variability, we used a crossover study design in volunteers.

Keywords

Plasma Concentration Muscle Relaxant Ulnar Nerve Vapor Concentration Neuromuscular Function 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Baurain MJ, et al. Anesthesiology 74:474, 1991PubMedCrossRefGoogle Scholar

Copyright information

© Springer Japan 1955

Authors and Affiliations

  • D. M. Fisher
    • 1
  • P. S. Hart
    • 1
  • P. M. C. Wright
    • 1
  • M. Lau
    • 1
  • R. Brown
    • 1
  • M. Sharma
    • 1
  1. 1.Department of AnesthesiaUniversity of CaliforniaSan FranciscoUSA

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