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Testicular Autoimmunity by Local Injury of the Testis in Experimental Animals

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Testicular Autoimmunity

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Abstract

Experimental autoimmune orchitis (EAO) can be induced by various local factors in the testis, without depending on systemic immunization with testicular antigens. The factors include traumatic injury, obstruction of germ cell transport, thermal injury, and foreign body injection, which induce a disruption of the BTB with the resultant exposure of TGC autoantigens to the immune system.

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  1. Department of Anatomy, Tokyo Medical University, Shinjyuku-ku, Tokyo, Japan

    Masahiro Itoh

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Itoh, M. (2017). Testicular Autoimmunity by Local Injury of the Testis in Experimental Animals. In: Testicular Autoimmunity. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54460-9_6

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