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Genexpressionsanalyse mit Microarrays

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Gentechnische Methoden

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Zusammenfassung

Das Prinzip der Microarray-Analyse beruht auf einer spezifischen Erkennung zweier DNA- oder RNAStränge. Ist die Sequenz einer Probe zu dem zu analysierenden RNA- oder DNA-Fragment komplementär, kann sie aufgrund der Watson-Crick-Basenpaarung selektiv hybridisieren. Die Detektion erfolgt anhand von Markierungen mit (Fluoreszenz-) Farbstoffen.

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Authors
  1. Susanne Kneitz
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Monika Jansohn Sophie Rothhämel

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© 2012 Spektrum Akademischer Verlag Heidelberg

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Kneitz, S. (2012). Genexpressionsanalyse mit Microarrays. In: Jansohn, M., Rothhämel, S. (eds) Gentechnische Methoden. Spektrum Akademischer Verlag, Heidelberg. https://doi.org/10.1007/978-3-8274-2430-3_19

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