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Radiotherapy for CNS GCTs

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Intracranial Germ Cell Tumors

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Abstract

At the time when open surgeries for pineal and hypothalamic-neurohypophyseal tumors showed high morbidity and mortality, irradiation was often used to determine the radiosensitivity of the tumor without histological confirmation. However, there is no longer any justification for the use of “diagnostic radiotherapy” or “radiation tests” in order to inspect the histologic nature of pineal and neurohypophyseal lesions. Radiotherapy should not be given before attempting to verify a tumor histology. Although the number of papers which stress the importance of histological diagnosis by surgery has been increasing, until recently the actual percentage of pathological verification before irradiation has been unsatisfactory in Japan [6]. Radiation oncologists should, therefore, encourage neurosurgeons to perform diagnostic or resection surgery for pineal and neurohypophyseal tumors. The reason for this recommendation will be described below.

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  1. Section of Radiation Oncology, Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan

    H. Shirato

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  1. Department of Neurosurgery, Hokkaido University School of Medicine, Sapporo, Japan

    Yutaka Sawamura

  2. Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan

    Hiroki Shirato

  3. Service de Neurochirurgie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

    Nicolas de Tribolet

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Shirato, H. (1998). Radiotherapy for CNS GCTs. In: Sawamura, Y., Shirato, H., de Tribolet, N. (eds) Intracranial Germ Cell Tumors. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6821-9_12

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