Zusammenfassung
Ein 75-jähriger Patient mit Diabetes Typ 2 seit 21 Jahren un bisher fehlenden Spätschäden möchte Empagliflozin. Wäre dies zu empfehlen?
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Literatur
Haring HU, Merker L, Seewaldt-Becker E, Weimer M, Meinicke T, Broedl UC, Woerle HJ, Investigators E-RMT (2014) Empagliflozin as add-on to metformin in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial. Diabetes care 37(6):1650–1659. https://doi.org/10.2337/dc13-2105
Haring HU, Merker L, Seewaldt-Becker E, Weimer M, Meinicke T, Woerle HJ, Broedl UC, Investigators E-RMT (2013) Empagliflozin as add-on to metformin plus sulfonylurea in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial. Diabetes care 36(11):3396–3404. https://doi.org/10.2337/dc12-2673
Kovacs CS, Seshiah V, Swallow R, Jones R, Rattunde H, Woerle HJ, Broedl UC, investigators E-RPt (2014) Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trial. Diabetes, obesity & metabolism 16(2):147–158. https://doi.org/10.1111/dom.12188
Ridderstrale M, Andersen KR, Zeller C, Kim G, Woerle HJ, Broedl UC, investigators E-RHHSt (2014) Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol 2(9):691–700. https://doi.org/10.1016/S2213-8587(14)70120-2
Roden M, Weng J, Eilbracht J, Delafont B, Kim G, Woerle HJ, Broedl UC, investigators E-RMt (2013) Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Diabetes Endocrinol 1(3):208–219. https://doi.org/10.1016/S2213-8587(13)70084-6
Rosenstock J, Jelaska A, Frappin G, Salsali A, Kim G, Woerle HJ, Broedl UC, Investigators E-RMT (2014) Improved glucose control with weight loss, lower insulin doses, and no increased hypoglycemia with empagliflozin added to titrated multiple daily injections of insulin in obese inadequately controlled type 2 diabetes. Diabetes care 37(7):1815–1823. https://doi.org/10.2337/dc13-3055
Rosenstock J, Jelaska A, Zeller C, Kim G, Broedl UC, Woerle HJ, investigators E-RBt (2015) Impact of empagliflozin added on to basal insulin in type 2 diabetes inadequately controlled on basal insulin: a 78-week randomized, double-blind, placebo-controlled trial. Diabetes, obesity & metabolism 17(10):936–948. https://doi.org/10.1111/dom.12503
Wanner C, Inzucchi SE, Lachin JM, Fitchett D, von Eynatten M, Mattheus M, Johansen OE, Woerle HJ, Broedl UC, Zinman B, Investigators E-RO (2016) Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes. New Engl J Med 375(4):323–334. https://doi.org/10.1056/NEJMoa1515920
Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Investigators E-RO, Broedl UC, Inzucchi SE (2015) Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. New Engl J Med 373(22):2117–2128. https://doi.org/10.1056/NEJMoa1504720
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Avranas, K. (2018). Fall 68: Therapie – 75 Jahre, ♂, DM Typ 2. In: Kihm, L., Kopf, S., Nawroth, P. (eds) Diabetes-Therapie – informiert entscheiden. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-55972-7_68
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DOI: https://doi.org/10.1007/978-3-662-55972-7_68
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