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Tumoren der Leber und Gallenblase

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Veterinäronkologie kompakt
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Zusammenfassung

Primäre Lebertumoren sind selten bei Tieren. Eine virale Ätiologie konnte für Murmeltiere (Woodchuck-Hepatitis-Virus), jedoch bislang weder für Hunde noch für Katzen identifiziert werden. Möglicherweise sind Infektionen mit Trematoden wie Ancylostoma caninum und Trichuris vulpis mit der Entwicklung von Gallengangskarzinomen assoziiert. Toxine, darunter Aflatoxine, induzieren zwar hepatozelluläre Karzinome, diese wurden bislang jedoch nur im Rahmen experimenteller Studien entwickelt. Im Gegensatz zum Menschen konnte bei Tieren bisher kein Zusammenhang zwischen Erkrankungen wie der Leberzirrhose oder Gallengangssteinen und der Entwicklung von Lebertumoren nachgewiesen werden.

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Weiterführende Literatur

  • Anderson LJ, Sandison AT (1968) Tumors of the liver in cattle, sheep and pigs. Cancer 21:289–301

    Article  PubMed  CAS  Google Scholar 

  • Balkman C (2009) Hepatobiliary neoplasia in dogs and cats. Vet Clin North Am Small Anim Pract 39:617–625

    Article  PubMed  Google Scholar 

  • Barr F (1995) Percutaneous biopsy of abdominal organs under ultrasound guidance. J Small Anim Pract 36:105–113

    Article  PubMed  CAS  Google Scholar 

  • Beeler-Marfisi J, Arroyo L, Caswell JL, Delay J, Bienzle D (2010) Equine primary liver tumors: a case series and review of the literature. J Vet Diagn Invest 22:174–183

    Article  PubMed  Google Scholar 

  • Bettini G, Marcato PS (1992) Primary hepatic tumours in cattle. A classification of 66 cases. J Comp Pathol 107:19–34

    Article  PubMed  CAS  Google Scholar 

  • Clifford CA, Pretorius ES, Weisse C, Sorenmo KU, Drobatz KJ, Siegelman ES, Solomon JA (2004) Magnetic resonance imaging of focal splenic and hepatic lesions in the dog. J Vet Intern Med 18:330–338

    Article  PubMed  Google Scholar 

  • Cohen M, Bohling MW, Wright JC, Welles EA, Spano JS (2003) Evaluation of sensitivity and specificity of cytologic examination: 269 cases (1999–2000). J Am Vet Med Assoc 222:964–967

    Article  PubMed  Google Scholar 

  • Cole TL, Center SA, Flood SN, Rowland PH, Valentine BA, Warner KL, Erb HN (2002) Diagnostic comparison of needle and wedge biopsy specimens of the liver in dogs and cats. J Am Vet Med Assoc 220:1483–1490

    Article  PubMed  Google Scholar 

  • Cullen JM, Popp JA (2002) Tumors in domestic animals, 4th Aufl. Iowa State Press, Ames

    Google Scholar 

  • De Vries C, Vanhaesebrouck E, Govaere J, Hoogewijs M, Bosseler L, Chiers K, Ducatelle R (2013) Congenital ascites due to hepatoblastoma with extensive peritoneal implantation metastases in a premature equine fetus. J Comp Pathol 148:214–219

    Article  PubMed  Google Scholar 

  • Elpiner AK, Brodsky EM, Hazzah TN, Post GS (2011) Single-agent gemcitabine chemotherapy in dogs with hepatocellular carcinomas. Vet Comp Oncol 9:260–268

    Article  PubMed  CAS  Google Scholar 

  • Haddad JL, Habecker PL (2012) Hepatocellular carcinomas in Vietnamese pot-bellied pigs (Sus scrofa). J Vet Diagn Invest 24:1047–1051.

    Article  PubMed  Google Scholar 

  • Hammer AS, Sikkema DA (1995) Hepatic neoplasia in the dog and cat. Vet Clin North Am Small Anim Pract 25:419–435

    Article  PubMed  CAS  Google Scholar 

  • Hayes HM, Morin MM, Rubenstein DA (1983) Canine biliary carcinoma: epidemiological comparisons with man. J Comp Pathol 93:99–107

    Article  PubMed  Google Scholar 

  • Kemp SD, Panciera DL, Larson MM, Saunders GK, Werre SR (2013) A comparison of hepatic sonographic features and histopathologic diagnosis in canine liver disease: 138 cases. J Vet Intern Med 27:806–813

    Article  PubMed  CAS  Google Scholar 

  • Kosovsky JE, Manframarretta S, Matthiesen DT, Patnaik AK (1989) Results of partial-hepatectomy in 18 dogs with hepatocellular-carcinoma. J Am Anim Hosp Assoc 25:203–206

    Google Scholar 

  • Kutara K, Asano K, Kito A, Teshima K, Kato Y, Sasaki Y, Edamura K, Shibuya H, Sato T, Hasegawa A, Tanaka S (2006) Contrast harmonic imaging of canine hepatic tumors. J Vet Med Sci 68:433–438

    Article  PubMed  Google Scholar 

  • Leveille R, Partington BP, Biller DS, Miyabayashi T (1993) Complications after ultrasound-guided biopsy of abdominal structures in dogs and cats – 246 cases (1984–1991). J Am Vet Med Assoc 203:413–415

    PubMed  CAS  Google Scholar 

  • Marconato L, Albanese F, Viacava P, Marchetti V, Abramo F (2007) Paraneoplastic alopecia associated with hepatocellular carcinoma in a cat. Vet Dermatol 18:267–271

    Article  PubMed  Google Scholar 

  • Nakamura K, Takagi S, Sasaki N, Kumara WRB, Murakami M, Ohta H, Yamasaki M, Takiguchi M (2010) Contrast-enhanced ultrasonography for characterization of canine focal liver lesions. Vet Radiol Ultrasound 51:79–85

    Article  PubMed  Google Scholar 

  • Newell SM, Selcer BA, Girard E, Roberts GD, Thompson JP, Harrison JM (1998) Correlations between ultrasonographic findings and specific hepatic diseases in cats: 72 cases (1985–1997). J Am Vet Med Assoc 213:94–98

    PubMed  CAS  Google Scholar 

  • Patnaik AK, Liu SK, Hurvitz AI, Mcclelland AJ (1975) Nonhematopoietic neoplasms in cats. J Natl Cancer Inst 54:855–860

    PubMed  CAS  Google Scholar 

  • Patnaik AK, Hurvitz AI, Lieberman PH (1980) Canine hepatic neoplasms: a clinicopathologic study. Vet Pathol 17:553–564

    Article  PubMed  CAS  Google Scholar 

  • Patnaik AK, Hurvitz AI, Lieberman PH, Johnson GF (1981a) Canine bile duct carcinoma. Vet Pathol 18:439–444

    Article  PubMed  CAS  Google Scholar 

  • Patnaik AK, Lieberman PH, Hurvitz AI, Johnson GF (1981b) Canine hepatic carcinoids. Vet Pathol 18:445–453

    Article  PubMed  CAS  Google Scholar 

  • Patnaik AK (1992) A morphologic and immunocytochemical study of hepatic neoplasms in cats. Vet Pathol 29:405–415

    Article  PubMed  CAS  Google Scholar 

  • Patnaik AK, Lieberman PH, Erlandson RA, Antonescu C (2005) Hepatobiliary neuroendocrine carcinoma in cats: a clinicopathologic, immunohistochemical, and ultrastructural study of 17 cases. Vet Pathol 42:331–337

    Article  PubMed  CAS  Google Scholar 

  • Roth L (2001) Comparison of liver cytology and biopsy diagnoses in dogs and cats: 56 cases. Vet Clin Pathol 30:35–38

    Article  PubMed  Google Scholar 

  • Stockhaus C, Van Den Ingh T, Rothuizen J, Teske E (2004) A multistep approach in the cytologic evaluation of liver biopsy samples of dogs with hepatic diseases. Vet Pathol 41:461–470

    Article  PubMed  CAS  Google Scholar 

  • Van Der Luer R, Van Den Ingh T, Van Hoe M (2008) Feline paraneoplastic alopecia. Tijdschr Diergeneeskd 133:182–183

    PubMed  Google Scholar 

  • Vörös K, Vrabely T, Papp L, Horvath L, Karsai F (1991) Correlation of ultrasonographic and pathomorphological findings in canine hepatic diseases. J Small Anim Pract 32:627–634

    Article  Google Scholar 

  • Yamada T, Fujita M, Kitao S, Ashida Y, Nishizono K, Tsuchiya R, Shida T, Kobayashi K (1999) Serum alpha-fetoprotein values in dogs with various hepatic diseases. J Vet Med Sci 61:657–659

    Article  PubMed  CAS  Google Scholar 

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Breithaupt, A. (2017). Tumoren der Leber und Gallenblase. In: Klopfleisch, R. (eds) Veterinäronkologie kompakt. Springer Spektrum, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54987-2_8

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  • DOI: https://doi.org/10.1007/978-3-662-54987-2_8

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