Abstract
The emergence of drug resistant fungal pathogens urgently calls for new generation of antifungal drugs with improved pharmacokinetics and pharmacodynamics. Antimicrobial peptides (AMPs) are mainly cationic and amphiphilic peptides composed of less than 50 amino acids, produced by diverse organisms for killing various kinds of invade bacteria, fungi, and viruses while have low cytotoxicity toward the organism themselves (Zasloff in Nature 415:389–395, 2002, [1]). Due to their new mechanisms of microbicidal action and scarce of resistance, they have been recognized as a gold mine of antimicrobial drugs.
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Wang, J. (2016). Biological Active Antifungal Peptides. In: Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification. Springer Theses. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53399-4_2
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DOI: https://doi.org/10.1007/978-3-662-53399-4_2
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