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Progesterontherapie zur Prävention der Frühgeburt

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Fehlgeburten Totgeburten Frühgeburten

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Zusammenfassung

Das Hormon Progesteron entfaltet eine Vielzahl von Wirkungen auf Myometrium und Zervix, u.a. eine Hemmung der Myometriumkontraktion und einen zervixstabilisierende Effekt. Es ist daher ein vielversprechender Kandidat zur Prävention der Frühgeburt. Die prophylaktische Gabe von Progesteron ist eine evidenzbasierte Maßnahme zur Prävention der Frühgeburt bei Frauen mit Einlingsschwangerschaft nach vorangegangener Frühgeburt sowie bei Schwangeren mit Einlingsschwangerschaft und Verkürzung der Zervix vor der 24. SSW. Inwieweit weitere Anwendungsmöglichkeiten bestehen (u.a. bei vorzeitiger Wehentätigkeit), wird derzeit in klinischen Studien überprüft.

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Authors and Affiliations

  1. Gynäkologishe Endokrinologie und Fertilitätsstörungen, Im Neuenheimer Feld 440, 69120, Heidelberg, Deutschland

    Ruben J. Kuon

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  1. Ruben J. Kuon
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Editors and Affiliations

  1. Gynäkologische Endokrinologie und Reproduktionsmedizin, Medizinische Universität Innsbruck, Innsbruck, Austria

    Bettina Toth

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Kuon, R.J. (2017). Progesterontherapie zur Prävention der Frühgeburt. In: Toth, B. (eds) Fehlgeburten Totgeburten Frühgeburten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-50424-6_29

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  • DOI: https://doi.org/10.1007/978-3-662-50424-6_29

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-50423-9

  • Online ISBN: 978-3-662-50424-6

  • eBook Packages: Medicine (German Language)

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